Detailed information NTG1168908

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACNUD3_RS11890
• Genome accession: NZ_OZ197082
• Coordinates: 2393465..2394814 (+)
• Length: 449 a.a.
• NCBI ID: WP_031775881.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate 23S00051-1
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	2387858..2403229	2393465..2394814	within	0

Gene organization within MGE regions

Location: 2387858..2403229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD3_RS11870	-	2387858..2389348 (-)	1491	WP_000554504.1	RNA-binding domain-containing protein	-
ACNUD3_RS11875	-	2389966..2391015 (-)	1050	WP_000613248.1	hypothetical protein	-
ACNUD3_RS11880	ssb	2391154..2391444 (+)	291	WP_001036437.1	cassette chromosome ssDNA-binding protein	-
ACNUD3_RS11885	cch1	2391444..2393231 (+)	1788	WP_000122621.1	cassette chromosome replicative helicase	-
ACNUD3_RS11890	ccrA	2393465..2394814 (+)	1350	WP_031775881.1	cassette chromosome recombinase CcrA	Machinery gene
ACNUD3_RS11895	ccrB	2394836..2396464 (+)	1629	WP_001186604.1	cassette chromosome recombinase CcrB	Machinery gene
ACNUD3_RS11900	-	2396986..2397336 (+)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACNUD3_RS11905	-	2397423..2397734 (+)	312	WP_000700851.1	DUF960 family protein	-
ACNUD3_RS11910	-	2397749..2398255 (+)	507	WP_001092189.1	DUF1643 domain-containing protein	-
ACNUD3_RS11915	-	2398304..2399914 (+)	1611	Protein_2302	IS1182 family transposase	-
ACNUD3_RS11920	-	2399905..2400147 (-)	243	Protein_2303	type I restriction enzyme endonuclease domain-containing protein	-
ACNUD3_RS11925	-	2400137..2401123 (-)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
ACNUD3_RS11930	mecA	2401220..2403229 (+)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52635.34 Da
• Isoelectric Point: 10.0472

>NTDB_id=1168908 ACNUD3_RS11890 WP_031775881.1 2393465..2394814(+) (ccrA) [Staphylococcus aureus isolate 23S00051-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1168908 ACNUD3_RS11890 WP_031775881.1 2393465..2394814(+) (ccrA) [Staphylococcus aureus isolate 23S00051-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-248)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.327	100	0.973
ccrA	Staphylococcus aureus COL	74.833	100	0.748