Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACNUDY_RS06330 Genome accession   NZ_OZ197081
Coordinates   1238430..1239146 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate 23S01946-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1233430..1244146
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNUDY_RS06300 - 1233699..1234325 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACNUDY_RS06305 - 1234633..1235418 (+) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  ACNUDY_RS06310 hld 1236018..1236098 (-) 81 WP_000046022.1 delta-hemolysin -
  ACNUDY_RS06315 agrB 1236388..1236957 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACNUDY_RS06320 agrD 1236954..1237094 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACNUDY_RS06325 agrC 1237119..1238411 (+) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  ACNUDY_RS06330 agrA 1238430..1239146 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACNUDY_RS06335 - 1239518..1240477 (-) 960 WP_001253294.1 carbohydrate kinase family protein -
  ACNUDY_RS06340 - 1240474..1241958 (-) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACNUDY_RS06345 - 1242107..1243057 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1168852 ACNUDY_RS06330 WP_000688492.1 1238430..1239146(+) (agrA) [Staphylococcus aureus isolate 23S01946-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1168852 ACNUDY_RS06330 WP_000688492.1 1238430..1239146(+) (agrA) [Staphylococcus aureus isolate 23S01946-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment