Detailed information NTG1168836

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACNUDY_RS01355
• Genome accession: NZ_OZ197081
• Coordinates: 279693..280667 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate 23S01946-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 274693..285667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDY_RS01320	rpmG	275153..275302 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACNUDY_RS01325	-	275511..276050 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACNUDY_RS01330	-	276062..277525 (+)	1464	WP_001017856.1	rhomboid family protein	-
ACNUDY_RS01335	-	277506..277709 (+)	204	WP_000087559.1	YqgQ family protein	-
ACNUDY_RS01340	-	277706..278692 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACNUDY_RS01345	-	278692..279021 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACNUDY_RS01350	-	279018..279641 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACNUDY_RS01355	comGA	279693..280667 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACNUDY_RS01360	comGB	280639..281709 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACNUDY_RS01365	-	281856..283026 (+)	1171	Protein_271	IS256-like element IS256 family transposase	-
ACNUDY_RS01370	-	283093..283239 (+)	147	WP_001789879.1	hypothetical protein	-
ACNUDY_RS01375	-	283229..283753 (+)	525	WP_001015120.1	shikimate kinase	-
ACNUDY_RS01380	gcvT	283912..285003 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1168836 ACNUDY_RS01355 WP_000697220.1 279693..280667(+) (comGA) [Staphylococcus aureus isolate 23S01946-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1168836 ACNUDY_RS01355 WP_000697220.1 279693..280667(+) (comGA) [Staphylococcus aureus isolate 23S01946-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1