Detailed information NTG1168816

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACNUDW_RS08095
• Genome accession: NZ_OZ197080
• Coordinates: 1635756..1636799 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 23S00032-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1630756..1641799

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDW_RS08065	-	1631177..1632433 (-)	1257	WP_074347694.1	aminopeptidase	-
ACNUDW_RS08070	-	1632436..1632636 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACNUDW_RS08075	-	1632783..1633247 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACNUDW_RS08080	-	1633254..1633529 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACNUDW_RS08085	-	1633807..1635024 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACNUDW_RS08090	vraR	1635137..1635766 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACNUDW_RS08095	vraS	1635756..1636799 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACNUDW_RS08100	liaF	1636796..1637497 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACNUDW_RS08105	-	1637512..1637898 (-)	387	WP_001110182.1	hypothetical protein	-
ACNUDW_RS08110	map	1638115..1638873 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
ACNUDW_RS08115	-	1639402..1640388 (+)	987	WP_000999712.1	FUSC family protein	-
ACNUDW_RS08120	-	1640577..1640990 (-)	414	WP_025174370.1	hypothetical protein	-
ACNUDW_RS08125	-	1641019..1641129 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1168816 ACNUDW_RS08095 WP_001017131.1 1635756..1636799(-) (vraS) [Staphylococcus aureus isolate 23S00032-1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1168816 ACNUDW_RS08095 WP_001017131.1 1635756..1636799(-) (vraS) [Staphylococcus aureus isolate 23S00032-1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1