Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AW02_RS05990 Genome accession   NZ_CP007165
Coordinates   1190896..1191552 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis NJN-6     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1185896..1196552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AW02_RS05965 (AW02_011380) oppF 1186424..1187341 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  AW02_RS05970 (AW02_011390) - 1187448..1188635 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  AW02_RS05975 (AW02_011400) - 1188754..1189332 (+) 579 WP_024085122.1 GNAT family N-acetyltransferase -
  AW02_RS05980 (AW02_011410) spx 1189511..1189906 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  AW02_RS05985 (AW02_011420) - 1189964..1190620 (-) 657 WP_003155033.1 TerC family protein -
  AW02_RS20660 - 1190803..1190913 (+) 111 Protein_1150 adaptor protein MecA -
  AW02_RS05990 (AW02_011430) mecA 1190896..1191552 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  AW02_RS05995 (AW02_011440) - 1191703..1192863 (+) 1161 WP_024085124.1 competence protein CoiA family protein -
  AW02_RS06000 (AW02_011450) pepF 1193091..1194920 (+) 1830 WP_024085125.1 oligoendopeptidase F Regulator
  AW02_RS20665 (AW02_011460) - 1194958..1195125 (-) 168 WP_003155026.1 hypothetical protein -
  AW02_RS06010 (AW02_011470) spxH 1195411..1196313 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=116698 AW02_RS05990 WP_003155032.1 1190896..1191552(+) (mecA) [Bacillus velezensis NJN-6]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=116698 AW02_RS05990 WP_003155032.1 1190896..1191552(+) (mecA) [Bacillus velezensis NJN-6]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTAGTGATCGCTGATCATGCGTTATATACAATAAAAA
AGCACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment