Detailed information NTG1166335

Bioinformatically predicted

Overview

• Name: pepF
• Type: Regulator
• Locus tag: AB3224_RS07090
• Genome accession: NZ_OZ061585
• Coordinates: 1438388..1440193 (-)
• Length: 601 a.a.
• NCBI ID: WP_015473911.1
• Uniprot ID: M5AFG0
• Organism: Levilactobacillus brevis isolate Levilactobacillus brevis CIRM-BIA2444
• Function: degradation of XIP; competence shut-off (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	1426760..1450099	1438388..1440193	within	0

Gene organization within MGE regions

Location: 1426760..1450099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3224_RS07030	-	1428357..1429286 (-)	930	WP_015473476.1	IS30-like element ISLpl1 family transposase	-
AB3224_RS07035	asp1	1429380..1430795 (-)	1416	WP_367370588.1	accessory Sec system glycosyltransferase Asp1	-
AB3224_RS07040	-	1430829..1431035 (-)	207	WP_015473902.1	hypothetical protein	-
AB3224_RS07045	-	1431051..1431413 (-)	363	WP_024855567.1	hypothetical protein	-
AB3224_RS07050	-	1431468..1431824 (-)	357	WP_021741809.1	hypothetical protein	-
AB3224_RS07055	-	1431856..1432245 (-)	390	WP_011668194.1	hypothetical protein	-
AB3224_RS07060	-	1432706..1433629 (+)	924	WP_041815392.1	IS30 family transposase	-
AB3224_RS07065	-	1433997..1434896 (-)	900	WP_011668196.1	RluA family pseudouridine synthase	-
AB3224_RS07070	-	1434893..1435696 (-)	804	WP_021740943.1	NAD kinase	-
AB3224_RS07075	-	1435698..1436357 (-)	660	WP_011668198.1	GTP pyrophosphokinase family protein	-
AB3224_RS07080	-	1436671..1437309 (+)	639	WP_011668199.1	ClpXP adapter SpxH family protein	-
AB3224_RS07085	-	1437471..1438334 (+)	864	WP_085769115.1	DegV family protein	-
AB3224_RS07090	pepF	1438388..1440193 (-)	1806	WP_015473911.1	oligoendopeptidase F	Regulator
AB3224_RS07095	-	1440260..1441354 (-)	1095	WP_015473912.1	competence protein CoiA	-
AB3224_RS07100	trmB	1441481..1442128 (-)	648	WP_015473913.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
AB3224_RS07105	-	1442194..1442985 (-)	792	WP_011668204.1	phosphotransferase family protein	-
AB3224_RS07110	-	1443047..1444273 (-)	1227	WP_011668205.1	ABC transporter permease	-
AB3224_RS07115	-	1444270..1445004 (-)	735	WP_011668206.1	ABC transporter ATP-binding protein	-
AB3224_RS07120	-	1445214..1445672 (+)	459	WP_011668207.1	HIT family protein	-
AB3224_RS07125	-	1445675..1445995 (+)	321	WP_015473917.1	hypothetical protein	-
AB3224_RS07130	-	1446108..1447025 (+)	918	WP_011668209.1	peptidylprolyl isomerase PrsA	-
AB3224_RS07135	-	1447089..1448063 (-)	975	WP_015473919.1	3'-5' exoribonuclease YhaM family protein	-

Sequence

Protein

• Length: 601 a.a.
• Molecular weight: 67135.10 Da
• Isoelectric Point: 4.7804

>NTDB_id=1166335 AB3224_RS07090 WP_015473911.1 1438388..1440193(-) (pepF) [Levilactobacillus brevis isolate Levilactobacillus brevis CIRM-BIA2444]
MKQIPKRSEVPTALTWDLTTIFPDEAAFKAAIAAIKTQTTVVAGLKGQLAQSGAALYRVTTAVFDLNRQLERVYVYASLN
NDQDTGNAAAQALMGQAESLVATVGAATAWFEPEVLALSADQLQTLIDNDPRLADYQHVFDVLGQQRAHTLSVAEEKLLA
GASDIFGASAKTYSVLSDADLKFPVVQDEAGNDVRLSEGLYGVLLQSTTPRVRQQAFEALYSVYQQFRHTFAATLASEVK
THNFSAETRHYASARAAAMSRNNVPAVVYDTLVETVNDHLDSLHRYVNLRKEILDLPQLHMYDLYTPITGEPSLKYTYQE
AQEMALKALAVLGPDYTANVQKMFDGRAIDVVENQGKRTGAYSGGMYDTKPYILLNWQDSLESLFTLVHEMGHSMHSHYT
RTNQPYQYGDYSIFVAEIASTTNENLLTDYLLKTQTDPKVRAYVLNHYLDGFKGTVYRQTQFAEFEDYIHQQDAAGETLT
ADFMSDFYGKLNQRYYGDGVISDPQIADEWTRIPHFYYDYYVYQYATGFAAATTLSQRILSGDEAKRDAYLAYLKAGSSA
LPLDVMKQAGVDMTQPGYLQTAFATFDERLAEFTQLAHELN

Nucleotide

• Length: 1806 bp

>NTDB_id=1166335 AB3224_RS07090 WP_015473911.1 1438388..1440193(-) (pepF) [Levilactobacillus brevis isolate Levilactobacillus brevis CIRM-BIA2444]
GTGAAACAAATTCCGAAACGATCAGAGGTTCCCACGGCACTGACTTGGGACCTGACAACTATTTTTCCCGACGAGGCAGC
TTTTAAGGCCGCAATTGCTGCAATTAAAACGCAAACAACGGTCGTGGCCGGTTTGAAGGGACAATTGGCCCAAAGTGGGG
CCGCGTTATATCGTGTCACGACGGCGGTATTTGATTTGAATCGCCAGTTGGAGCGGGTATATGTCTATGCGTCTTTAAAC
AATGATCAGGATACCGGCAATGCTGCAGCCCAGGCATTAATGGGGCAGGCCGAGAGCTTGGTGGCAACTGTGGGTGCCGC
CACGGCTTGGTTTGAACCTGAGGTATTGGCCTTGTCAGCGGATCAGCTGCAAACGTTGATTGATAACGACCCCCGGCTAG
CAGATTATCAGCATGTGTTTGACGTATTGGGCCAGCAGCGGGCACATACGCTGTCAGTGGCGGAAGAAAAATTGCTAGCG
GGTGCTAGTGATATCTTTGGTGCATCTGCTAAAACTTACAGCGTGCTGAGTGATGCTGATCTAAAGTTTCCAGTTGTTCA
AGACGAAGCCGGCAATGATGTGCGACTGTCAGAAGGACTGTATGGTGTTTTGCTACAATCCACAACACCACGGGTGCGGC
AGCAGGCTTTTGAAGCATTATATTCGGTTTATCAACAATTCCGACATACCTTTGCTGCAACCTTAGCGAGCGAAGTCAAA
ACGCATAATTTTAGTGCTGAGACGCGTCACTATGCGAGTGCCAGAGCGGCAGCGATGAGTCGCAACAATGTGCCAGCGGT
GGTCTATGATACCTTGGTGGAAACAGTCAATGATCATTTAGACTCACTGCATCGCTATGTTAATTTGCGCAAAGAGATTT
TGGACTTGCCACAACTGCACATGTACGACCTGTATACGCCAATTACGGGTGAACCCAGCTTGAAATATACCTACCAAGAA
GCACAAGAGATGGCGTTAAAGGCACTAGCAGTCTTGGGACCGGATTACACTGCCAATGTTCAAAAGATGTTTGATGGCCG
GGCAATTGATGTGGTTGAAAATCAGGGTAAACGGACGGGCGCTTACTCAGGCGGGATGTATGATACTAAACCGTATATTT
TGTTGAATTGGCAAGATAGCTTGGAAAGCTTGTTCACGTTGGTTCATGAGATGGGACACAGCATGCATAGCCATTACACT
CGGACAAATCAACCGTACCAGTATGGTGATTATTCAATCTTTGTTGCGGAAATTGCCTCGACAACGAATGAAAACTTGCT
GACGGACTACCTGTTGAAAACCCAGACTGACCCCAAGGTGCGAGCTTATGTATTAAATCATTATCTGGATGGCTTTAAAG
GCACGGTATACCGCCAGACGCAGTTCGCAGAATTTGAGGACTACATTCACCAACAGGATGCCGCTGGCGAAACTCTGACA
GCTGACTTCATGAGTGATTTCTACGGCAAACTTAATCAGCGTTATTACGGTGATGGCGTGATTTCCGATCCACAAATCGC
TGATGAATGGACCCGAATTCCACATTTCTACTATGACTACTATGTGTACCAGTACGCAACCGGGTTTGCGGCGGCCACGA
CGTTATCGCAACGAATTTTGAGTGGCGACGAGGCAAAGCGGGATGCCTACTTGGCCTATCTAAAGGCGGGAAGTTCTGCC
TTACCACTTGATGTGATGAAACAAGCGGGCGTCGATATGACGCAACCGGGCTATTTGCAAACGGCTTTTGCAACGTTCGA
CGAGCGCTTGGCAGAATTCACGCAATTGGCGCATGAATTAAACTAA

Domains

Predicted by InterproScan.

• Oligopeptidase F (Peptidase_M3_N) (114-183)

• Peptidase family M3 (Peptidase_M3) (204-584)

3D structure

• AlphaFold DB: M5AFG0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pepF	Streptococcus salivarius strain HSISS4	49.831	98.17	0.489