Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   AB3221_RS06445 Genome accession   NZ_OZ061323
Coordinates   1252433..1253104 (-) Length   223 a.a.
NCBI ID   WP_004270751.1    Uniprot ID   A0A1B2A7J9
Organism   Latilactobacillus curvatus isolate Latilactobacillus curvatus CIRM-BIA2781     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1247433..1258104
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3221_RS06430 holA 1248602..1249630 (-) 1029 WP_148484641.1 DNA polymerase III subunit delta -
  AB3221_RS06435 comEC 1249631..1251745 (-) 2115 WP_262346498.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AB3221_RS06440 - 1251886..1252374 (-) 489 WP_126133318.1 ComE operon protein 2 -
  AB3221_RS06445 comEA 1252433..1253104 (-) 672 WP_004270751.1 helix-hairpin-helix domain-containing protein Machinery gene
  AB3221_RS06450 - 1253181..1254227 (-) 1047 WP_367370108.1 SepM family pheromone-processing serine protease -
  AB3221_RS06455 coaD 1254229..1254723 (-) 495 WP_065825725.1 pantetheine-phosphate adenylyltransferase -
  AB3221_RS06460 rsmD 1254735..1255289 (-) 555 WP_004270750.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AB3221_RS06465 - 1255295..1255585 (-) 291 WP_004270748.1 YlbG family protein -
  AB3221_RS06470 - 1255605..1256693 (-) 1089 WP_223315706.1 CAP-associated domain-containing protein -
  AB3221_RS06475 - 1256706..1257893 (-) 1188 WP_004270744.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24849.51 Da        Isoelectric Point: 9.9048

>NTDB_id=1165867 AB3221_RS06445 WP_004270751.1 1252433..1253104(-) (comEA) [Latilactobacillus curvatus isolate Latilactobacillus curvatus CIRM-BIA2781]
MWRDYWQRYRRFWWVPCLVIILLGGGVFWQHSRQQRFLSTNQQLMAQSTKRKVKAKPVKQKKSVSKGGFVDIKGAVAHPG
IYPICVAKTRLFEVLKQAGDVTEAADTSQLNLAQTLSDQLIIYVPTKGEAVQAEELVKAADEPQAATDNQAGASPISTDA
KINLNQADATQLQTLNGIGPKKAEQIIAYRDEQGQFKQIEDLQKVGGIGPKTFEQLRPQICVN

Nucleotide


Download         Length: 672 bp        

>NTDB_id=1165867 AB3221_RS06445 WP_004270751.1 1252433..1253104(-) (comEA) [Latilactobacillus curvatus isolate Latilactobacillus curvatus CIRM-BIA2781]
ATGTGGCGCGACTATTGGCAACGGTATCGTCGATTCTGGTGGGTACCTTGTTTGGTGATAATTTTACTTGGTGGTGGTGT
GTTTTGGCAGCATAGTCGGCAACAACGTTTTCTATCAACCAATCAACAATTGATGGCGCAATCAACTAAGCGAAAAGTGA
AGGCAAAACCCGTCAAACAGAAGAAAAGCGTCTCAAAAGGTGGGTTTGTCGATATCAAAGGCGCTGTGGCACATCCAGGG
ATTTATCCGATTTGTGTTGCAAAGACGCGTTTATTTGAGGTGCTGAAACAAGCTGGGGATGTGACCGAAGCAGCGGATAC
GAGTCAGTTGAACTTAGCGCAAACATTGAGTGACCAACTTATTATCTATGTGCCAACTAAGGGAGAAGCGGTGCAAGCCG
AAGAATTAGTGAAAGCGGCAGACGAGCCACAGGCTGCGACTGACAATCAAGCGGGAGCCAGTCCGATATCAACTGATGCT
AAAATCAACCTAAACCAAGCGGATGCGACACAATTGCAAACGCTAAATGGCATCGGTCCTAAAAAAGCTGAACAAATAAT
TGCATATCGGGATGAGCAAGGGCAGTTTAAACAAATCGAAGATCTTCAAAAAGTTGGGGGAATTGGGCCGAAAACGTTTG
AACAATTACGGCCACAAATTTGTGTTAATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(70-115)

Helix-hairpin-helix motif (HHH_3)

(160-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B2A7J9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Latilactobacillus sakei subsp. sakei 23K

64.53

100

0.677
  comEA Lactococcus lactis subsp. cremoris KW2

36.283

100

0.368

Multiple sequence alignment