Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   AB3Y84_RS11345 Genome accession   NZ_OZ061291
Coordinates   2282337..2283365 (-) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis isolate Lactococcus lactis CIRM-BIA2553     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2277337..2288365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3Y84_RS11325 - 2280244..2281110 (-) 867 Protein_2196 ATP-binding cassette domain-containing protein -
  AB3Y84_RS11330 - 2281194..2281376 (-) 183 WP_367294015.1 hypothetical protein -
  AB3Y84_RS11335 - 2281381..2281830 (-) 450 WP_367294016.1 hypothetical protein -
  AB3Y84_RS11340 - 2281823..2282221 (-) 399 WP_098384274.1 SPASM domain-containing protein -
  AB3Y84_RS11345 sepM 2282337..2283365 (-) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  AB3Y84_RS11350 coaD 2283352..2283849 (-) 498 WP_367294017.1 pantetheine-phosphate adenylyltransferase -
  AB3Y84_RS11355 rsmD 2283897..2284436 (-) 540 WP_367294050.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AB3Y84_RS11360 - 2284606..2285826 (-) 1221 WP_098384275.1 MFS transporter -
  AB3Y84_RS11365 lmrP 2285910..2287136 (-) 1227 WP_098384276.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=1165725 AB3Y84_RS11345 WP_003132657.1 2282337..2283365(-) (sepM) [Lactococcus lactis isolate Lactococcus lactis CIRM-BIA2553]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=1165725 AB3Y84_RS11345 WP_003132657.1 2282337..2283365(-) (sepM) [Lactococcus lactis isolate Lactococcus lactis CIRM-BIA2553]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491

Multiple sequence alignment