Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   AB3Y84_RS08205 Genome accession   NZ_OZ061291
Coordinates   1669882..1671357 (-) Length   491 a.a.
NCBI ID   WP_010906048.1    Uniprot ID   A0A2A9ICZ0
Organism   Lactococcus lactis isolate Lactococcus lactis CIRM-BIA2553     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1664882..1676357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3Y84_RS08185 murG 1665020..1666093 (-) 1074 WP_367293900.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  AB3Y84_RS08190 murD 1666284..1667654 (-) 1371 WP_098383981.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  AB3Y84_RS08195 - 1667985..1668326 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  AB3Y84_RS08200 - 1668458..1669699 (-) 1242 WP_015426746.1 ammonium transporter -
  AB3Y84_RS08205 covS 1669882..1671357 (-) 1476 WP_010906048.1 HAMP domain-containing histidine kinase Regulator
  AB3Y84_RS08210 covR 1671365..1672057 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  AB3Y84_RS08215 - 1672213..1672743 (-) 531 WP_021722680.1 DUF177 domain-containing protein -
  AB3Y84_RS08220 - 1672874..1673119 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  AB3Y84_RS08225 - 1673275..1673739 (-) 465 WP_017864799.1 hypothetical protein -
  AB3Y84_RS08230 - 1673821..1674183 (-) 363 WP_010906050.1 TIGR02328 family protein -
  AB3Y84_RS08235 - 1674667..1675197 (-) 531 WP_179884488.1 CHAP domain-containing protein -
  AB3Y84_RS08240 - 1675259..1676095 (-) 837 WP_023164354.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56195.08 Da        Isoelectric Point: 4.8253

>NTDB_id=1165701 AB3Y84_RS08205 WP_010906048.1 1669882..1671357(-) (covS) [Lactococcus lactis isolate Lactococcus lactis CIRM-BIA2553]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=1165701 AB3Y84_RS08205 WP_010906048.1 1669882..1671357(-) (covS) [Lactococcus lactis isolate Lactococcus lactis CIRM-BIA2553]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATAAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCGAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A9ICZ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

100

100

1

Multiple sequence alignment