Detailed information NTG1165408

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACE4RH_RS14750
• Genome accession: NZ_OZ059824
• Coordinates: 2916226..2917575 (-)
• Length: 449 a.a.
• NCBI ID: WP_031775881.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate E3_22S00626-1
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	2907810..2923182	2916226..2917575	within	0

Gene organization within MGE regions

Location: 2907810..2923182

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RH_RS14710	mecA	2907810..2909819 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
ACE4RH_RS14715	-	2909916..2910902 (+)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
ACE4RH_RS14720	-	2910889..2911134 (+)	246	Protein_2861	type I restriction enzyme endonuclease domain-containing protein	-
ACE4RH_RS14725	-	2911125..2912735 (-)	1611	Protein_2862	IS1182 family transposase	-
ACE4RH_RS14730	-	2912784..2913290 (-)	507	WP_001092189.1	DUF1643 domain-containing protein	-
ACE4RH_RS14735	-	2913305..2913616 (-)	312	WP_000700851.1	DUF960 family protein	-
ACE4RH_RS14740	-	2913703..2914053 (-)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACE4RH_RS14745	ccrB	2914576..2916204 (-)	1629	WP_001186604.1	cassette chromosome recombinase CcrB	Machinery gene
ACE4RH_RS14750	ccrA	2916226..2917575 (-)	1350	WP_031775881.1	cassette chromosome recombinase CcrA	Machinery gene
ACE4RH_RS14755	cch1	2917809..2919596 (-)	1788	WP_000122621.1	cassette chromosome replicative helicase	-
ACE4RH_RS14760	ssb	2919596..2919886 (-)	291	WP_001036437.1	cassette chromosome ssDNA-binding protein	-
ACE4RH_RS14765	-	2920025..2921074 (+)	1050	WP_000613248.1	hypothetical protein	-
ACE4RH_RS14770	-	2921692..2923182 (+)	1491	WP_000554504.1	RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52635.34 Da
• Isoelectric Point: 10.0472

>NTDB_id=1165408 ACE4RH_RS14750 WP_031775881.1 2916226..2917575(-) (ccrA) [Staphylococcus aureus isolate E3_22S00626-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1165408 ACE4RH_RS14750 WP_031775881.1 2916226..2917575(-) (ccrA) [Staphylococcus aureus isolate E3_22S00626-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-248)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.327	100	0.973
ccrA	Staphylococcus aureus COL	74.833	100	0.748