Detailed information NTG1165383

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACE4RH_RS05990
• Genome accession: NZ_OZ059824
• Coordinates: 1188584..1189558 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate E3_22S00626-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1183584..1194558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RH_RS05955	rpmG	1184044..1184193 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACE4RH_RS05960	-	1184402..1184941 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACE4RH_RS05965	-	1184953..1186416 (+)	1464	WP_001017856.1	rhomboid family intramembrane serine protease	-
ACE4RH_RS05970	-	1186397..1186600 (+)	204	WP_000087559.1	YqgQ family protein	-
ACE4RH_RS05975	-	1186597..1187583 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACE4RH_RS05980	-	1187583..1187912 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACE4RH_RS05985	-	1187909..1188532 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACE4RH_RS05990	comGA	1188584..1189558 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACE4RH_RS05995	comGB	1189530..1190600 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACE4RH_RS06000	-	1190747..1191917 (+)	1171	Protein_1176	IS256-like element IS256 family transposase	-
ACE4RH_RS06005	-	1191984..1192130 (+)	147	WP_001789879.1	hypothetical protein	-
ACE4RH_RS06010	-	1192120..1192644 (+)	525	WP_001015120.1	shikimate kinase	-
ACE4RH_RS06015	gcvT	1192803..1193894 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1165383 ACE4RH_RS05990 WP_000697220.1 1188584..1189558(+) (comGA) [Staphylococcus aureus isolate E3_22S00626-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1165383 ACE4RH_RS05990 WP_000697220.1 1188584..1189558(+) (comGA) [Staphylococcus aureus isolate E3_22S00626-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1