Detailed information NTG1165351

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACE4RD_RS09925
• Genome accession: NZ_OZ059823
• Coordinates: 1988381..1989355 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate E2_22S00623-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1983381..1994355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RD_RS09890	rpmG	1983841..1983990 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACE4RD_RS09895	-	1984199..1984738 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACE4RD_RS09900	-	1984750..1986213 (+)	1464	WP_001017856.1	rhomboid family intramembrane serine protease	-
ACE4RD_RS09905	-	1986194..1986397 (+)	204	WP_000087559.1	YqgQ family protein	-
ACE4RD_RS09910	-	1986394..1987380 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACE4RD_RS09915	-	1987380..1987709 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACE4RD_RS09920	-	1987706..1988329 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACE4RD_RS09925	comGA	1988381..1989355 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACE4RD_RS09930	comGB	1989327..1990397 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACE4RD_RS09935	-	1990544..1991714 (+)	1171	Protein_1947	IS256-like element IS256 family transposase	-
ACE4RD_RS09940	-	1991781..1991927 (+)	147	WP_001789879.1	hypothetical protein	-
ACE4RD_RS09945	-	1991917..1992441 (+)	525	WP_001015120.1	shikimate kinase	-
ACE4RD_RS09950	gcvT	1992600..1993691 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1165351 ACE4RD_RS09925 WP_000697220.1 1988381..1989355(+) (comGA) [Staphylococcus aureus isolate E2_22S00623-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1165351 ACE4RD_RS09925 WP_000697220.1 1988381..1989355(+) (comGA) [Staphylococcus aureus isolate E2_22S00623-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1