Detailed information NTG1165334

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACE4RD_RS03885
• Genome accession: NZ_OZ059823
• Coordinates: 788125..789474 (-)
• Length: 449 a.a.
• NCBI ID: WP_031775881.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate E2_22S00623-1
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	779709..795081	788125..789474	within	0

Gene organization within MGE regions

Location: 779709..795081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RD_RS03845	mecA	779709..781718 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
ACE4RD_RS03850	-	781815..782801 (+)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
ACE4RD_RS03855	-	782788..783033 (+)	246	Protein_754	type I restriction enzyme endonuclease domain-containing protein	-
ACE4RD_RS03860	-	783024..784634 (-)	1611	Protein_755	IS1182 family transposase	-
ACE4RD_RS03865	-	784683..785189 (-)	507	WP_001092189.1	DUF1643 domain-containing protein	-
ACE4RD_RS03870	-	785204..785515 (-)	312	WP_000700851.1	DUF960 family protein	-
ACE4RD_RS03875	-	785602..785952 (-)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACE4RD_RS03880	ccrB	786475..788103 (-)	1629	WP_001186604.1	cassette chromosome recombinase CcrB	Machinery gene
ACE4RD_RS03885	ccrA	788125..789474 (-)	1350	WP_031775881.1	cassette chromosome recombinase CcrA	Machinery gene
ACE4RD_RS03890	cch1	789708..791495 (-)	1788	WP_000122621.1	cassette chromosome replicative helicase	-
ACE4RD_RS03895	ssb	791495..791785 (-)	291	WP_001036437.1	cassette chromosome ssDNA-binding protein	-
ACE4RD_RS03900	-	791924..792973 (+)	1050	WP_000613248.1	hypothetical protein	-
ACE4RD_RS03905	-	793591..795081 (+)	1491	WP_000554504.1	RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52635.34 Da
• Isoelectric Point: 10.0472

>NTDB_id=1165334 ACE4RD_RS03885 WP_031775881.1 788125..789474(-) (ccrA) [Staphylococcus aureus isolate E2_22S00623-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1165334 ACE4RD_RS03885 WP_031775881.1 788125..789474(-) (ccrA) [Staphylococcus aureus isolate E2_22S00623-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-248)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.327	100	0.973
ccrA	Staphylococcus aureus COL	74.833	100	0.748