Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACE4RE_RS07295 Genome accession   NZ_OZ059822
Coordinates   1489883..1490599 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate E9_23S01315-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484883..1495599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE4RE_RS07280 - 1485972..1486922 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  ACE4RE_RS07285 - 1487071..1488555 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACE4RE_RS07290 - 1488552..1489511 (+) 960 WP_001253294.1 carbohydrate kinase -
  ACE4RE_RS07295 agrA 1489883..1490599 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACE4RE_RS07300 agrC 1490618..1491910 (-) 1293 WP_374749763.1 quorum-sensing sensor histidine kinase AgrC -
  ACE4RE_RS07305 agrD 1491935..1492075 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACE4RE_RS07310 agrB 1492072..1492641 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACE4RE_RS07315 hld 1492931..1493011 (+) 81 WP_000046022.1 delta-hemolysin -
  ACE4RE_RS07320 - 1493612..1494397 (-) 786 WP_374749764.1 carbon-nitrogen family hydrolase -
  ACE4RE_RS07325 - 1494705..1495331 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1165294 ACE4RE_RS07295 WP_000688492.1 1489883..1490599(-) (agrA) [Staphylococcus aureus isolate E9_23S01315-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1165294 ACE4RE_RS07295 WP_000688492.1 1489883..1490599(-) (agrA) [Staphylococcus aureus isolate E9_23S01315-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment