Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACE4RJ_RS13395 Genome accession   NZ_OZ059821
Coordinates   2701277..2701993 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate H3_23S01314-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2696277..2706993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE4RJ_RS13365 - 2696546..2697172 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACE4RJ_RS13370 - 2697480..2698265 (+) 786 WP_374749764.1 carbon-nitrogen family hydrolase -
  ACE4RJ_RS13375 hld 2698865..2698945 (-) 81 WP_000046022.1 delta-hemolysin -
  ACE4RJ_RS13380 agrB 2699235..2699804 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACE4RJ_RS13385 agrD 2699801..2699941 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACE4RJ_RS13390 agrC 2699966..2701258 (+) 1293 WP_374749763.1 quorum-sensing sensor histidine kinase AgrC -
  ACE4RJ_RS13395 agrA 2701277..2701993 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACE4RJ_RS13400 - 2702365..2703324 (-) 960 WP_001253294.1 carbohydrate kinase -
  ACE4RJ_RS13405 - 2703321..2704805 (-) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACE4RJ_RS13410 - 2704954..2705904 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1165276 ACE4RJ_RS13395 WP_000688492.1 2701277..2701993(+) (agrA) [Staphylococcus aureus isolate H3_23S01314-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1165276 ACE4RJ_RS13395 WP_000688492.1 2701277..2701993(+) (agrA) [Staphylococcus aureus isolate H3_23S01314-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment