Detailed information NTG1165275

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACE4RJ_RS12945
• Genome accession: NZ_OZ059821
• Coordinates: 2612641..2613684 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate H3_23S01314-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2607641..2618684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RJ_RS12915	-	2608062..2609318 (-)	1257	WP_074347694.1	aminopeptidase	-
ACE4RJ_RS12920	-	2609321..2609521 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACE4RJ_RS12925	-	2609668..2610132 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACE4RJ_RS12930	-	2610139..2610414 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACE4RJ_RS12935	-	2610692..2611909 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACE4RJ_RS12940	vraR	2612022..2612651 (-)	630	WP_374750092.1	two-component system response regulator VraR	Regulator
ACE4RJ_RS12945	vraS	2612641..2613684 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACE4RJ_RS12950	liaF	2613681..2614382 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACE4RJ_RS12955	-	2614397..2614783 (-)	387	WP_001110182.1	hypothetical protein	-
ACE4RJ_RS12960	map	2615000..2615758 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
ACE4RJ_RS12965	-	2616342..2617328 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
ACE4RJ_RS12970	-	2617517..2617930 (-)	414	WP_025174370.1	hypothetical protein	-
ACE4RJ_RS12975	-	2617959..2618069 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1165275 ACE4RJ_RS12945 WP_001017131.1 2612641..2613684(-) (vraS) [Staphylococcus aureus isolate H3_23S01314-1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1165275 ACE4RJ_RS12945 WP_001017131.1 2612641..2613684(-) (vraS) [Staphylococcus aureus isolate H3_23S01314-1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1