Detailed information NTG1165218

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACE4RI_RS10035
• Genome accession: NZ_OZ059820
• Coordinates: 2011745..2012719 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate E1_22S00622-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2006745..2017719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RI_RS10000	rpmG	2007205..2007354 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACE4RI_RS10005	-	2007563..2008102 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACE4RI_RS10010	-	2008114..2009577 (+)	1464	WP_001017856.1	rhomboid family intramembrane serine protease	-
ACE4RI_RS10015	-	2009558..2009761 (+)	204	WP_000087559.1	YqgQ family protein	-
ACE4RI_RS10020	-	2009758..2010744 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACE4RI_RS10025	-	2010744..2011073 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACE4RI_RS10030	-	2011070..2011693 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACE4RI_RS10035	comGA	2011745..2012719 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACE4RI_RS10040	comGB	2012691..2013761 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACE4RI_RS10045	-	2013908..2015078 (+)	1171	Protein_1969	IS256-like element IS256 family transposase	-
ACE4RI_RS10050	-	2015145..2015291 (+)	147	WP_001789879.1	hypothetical protein	-
ACE4RI_RS10055	-	2015281..2015805 (+)	525	WP_001015120.1	shikimate kinase	-
ACE4RI_RS10060	gcvT	2015964..2017055 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1165218 ACE4RI_RS10035 WP_000697220.1 2011745..2012719(+) (comGA) [Staphylococcus aureus isolate E1_22S00622-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1165218 ACE4RI_RS10035 WP_000697220.1 2011745..2012719(+) (comGA) [Staphylococcus aureus isolate E1_22S00622-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1