Detailed information NTG1165142

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACE4RB_RS13225
• Genome accession: NZ_OZ059818
• Coordinates: 2605835..2606809 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate E4_22S00627-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2600835..2611809

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RB_RS13190	rpmG	2601295..2601444 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACE4RB_RS13195	-	2601653..2602192 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACE4RB_RS13200	-	2602204..2603667 (+)	1464	WP_001017856.1	rhomboid family intramembrane serine protease	-
ACE4RB_RS13205	-	2603648..2603851 (+)	204	WP_000087559.1	YqgQ family protein	-
ACE4RB_RS13210	-	2603848..2604834 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACE4RB_RS13215	-	2604834..2605163 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACE4RB_RS13220	-	2605160..2605783 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACE4RB_RS13225	comGA	2605835..2606809 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACE4RB_RS13230	comGB	2606781..2607851 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACE4RB_RS13235	-	2607998..2609168 (+)	1171	Protein_2565	IS256-like element IS256 family transposase	-
ACE4RB_RS13240	-	2609235..2609381 (+)	147	WP_001789879.1	hypothetical protein	-
ACE4RB_RS13245	-	2609371..2609895 (+)	525	WP_001015120.1	shikimate kinase	-
ACE4RB_RS13250	gcvT	2610054..2611145 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1165142 ACE4RB_RS13225 WP_000697220.1 2605835..2606809(+) (comGA) [Staphylococcus aureus isolate E4_22S00627-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1165142 ACE4RB_RS13225 WP_000697220.1 2605835..2606809(+) (comGA) [Staphylococcus aureus isolate E4_22S00627-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1