Detailed information NTG1165120

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACE4RB_RS06535
• Genome accession: NZ_OZ059818
• Coordinates: 1252047..1252934 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate E4_22S00627-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1247047..1257934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RB_RS06505	-	1247058..1247150 (+)	93	WP_031774855.1	hypothetical protein	-
ACE4RB_RS06510	-	1247258..1247755 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACE4RB_RS06515	-	1247765..1248025 (-)	261	WP_014937088.1	hypothetical protein	-
ACE4RB_RS06520	-	1248407..1248520 (-)	114	WP_014937089.1	hypothetical protein	-
ACE4RB_RS06525	-	1249187..1251187 (-)	2001	WP_000776741.1	ABC transporter permease	-
ACE4RB_RS06530	-	1251184..1251939 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACE4RB_RS06535	braS	1252047..1252934 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACE4RB_RS06540	braR	1252945..1253610 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACE4RB_RS06545	-	1253636..1253836 (-)	201	WP_000604731.1	hypothetical protein	-
ACE4RB_RS06550	-	1254034..1255458 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACE4RB_RS06555	-	1255518..1255619 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACE4RB_RS06560	-	1255741..1256196 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACE4RB_RS06565	-	1256441..1257202 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1165120 ACE4RB_RS06535 WP_000143420.1 1252047..1252934(-) (braS) [Staphylococcus aureus isolate E4_22S00627-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1165120 ACE4RB_RS06535 WP_000143420.1 1252047..1252934(-) (braS) [Staphylococcus aureus isolate E4_22S00627-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993