Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACE4RB_RS03375 Genome accession   NZ_OZ059818
Coordinates   632618..633334 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate E4_22S00627-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 627618..638334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE4RB_RS03345 - 627887..628513 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACE4RB_RS03350 - 628821..629606 (+) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  ACE4RB_RS03355 hld 630206..630286 (-) 81 WP_000046022.1 delta-hemolysin -
  ACE4RB_RS03360 agrB 630576..631145 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACE4RB_RS03365 agrD 631142..631282 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACE4RB_RS03370 agrC 631307..632599 (+) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  ACE4RB_RS03375 agrA 632618..633334 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACE4RB_RS03380 - 633706..634665 (-) 960 WP_001253294.1 carbohydrate kinase -
  ACE4RB_RS03385 - 634662..636146 (-) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACE4RB_RS03390 - 636295..637245 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1165116 ACE4RB_RS03375 WP_000688492.1 632618..633334(+) (agrA) [Staphylococcus aureus isolate E4_22S00627-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1165116 ACE4RB_RS03375 WP_000688492.1 632618..633334(+) (agrA) [Staphylococcus aureus isolate E4_22S00627-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment