Detailed information NTG1165103

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACE4RF_RS12865
• Genome accession: NZ_OZ059817
• Coordinates: 2588083..2588970 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate E6_22S00629-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2583083..2593970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RF_RS12835	-	2583815..2584576 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
ACE4RF_RS12840	-	2584821..2585276 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACE4RF_RS12845	-	2585398..2585499 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACE4RF_RS12850	-	2585559..2586983 (-)	1425	WP_031872430.1	alkaline phosphatase	-
ACE4RF_RS12855	-	2587181..2587381 (+)	201	WP_000604731.1	hypothetical protein	-
ACE4RF_RS12860	braR	2587407..2588072 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACE4RF_RS12865	braS	2588083..2588970 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACE4RF_RS12870	-	2589078..2589833 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACE4RF_RS12875	-	2589830..2591830 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACE4RF_RS12880	-	2592497..2592610 (+)	114	WP_014937089.1	hypothetical protein	-
ACE4RF_RS12885	-	2592992..2593252 (+)	261	WP_014937088.1	hypothetical protein	-
ACE4RF_RS12890	-	2593262..2593759 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACE4RF_RS12895	-	2593867..2593959 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1165103 ACE4RF_RS12865 WP_000143420.1 2588083..2588970(+) (braS) [Staphylococcus aureus isolate E6_22S00629-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1165103 ACE4RF_RS12865 WP_000143420.1 2588083..2588970(+) (braS) [Staphylococcus aureus isolate E6_22S00629-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993