Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACE4RF_RS01840 Genome accession   NZ_OZ059817
Coordinates   351456..352172 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate E6_22S00629-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 346456..357172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE4RF_RS01825 - 347545..348495 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  ACE4RF_RS01830 - 348644..350128 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACE4RF_RS01835 - 350125..351084 (+) 960 WP_001253294.1 carbohydrate kinase -
  ACE4RF_RS01840 agrA 351456..352172 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACE4RF_RS01845 agrC 352191..353483 (-) 1293 WP_374749763.1 quorum-sensing sensor histidine kinase AgrC -
  ACE4RF_RS01850 agrD 353508..353648 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACE4RF_RS01855 agrB 353645..354214 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACE4RF_RS01860 hld 354504..354584 (+) 81 WP_000046022.1 delta-hemolysin -
  ACE4RF_RS01865 - 355185..355970 (-) 786 WP_374749764.1 carbon-nitrogen family hydrolase -
  ACE4RF_RS01870 - 356278..356904 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1165061 ACE4RF_RS01840 WP_000688492.1 351456..352172(-) (agrA) [Staphylococcus aureus isolate E6_22S00629-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1165061 ACE4RF_RS01840 WP_000688492.1 351456..352172(-) (agrA) [Staphylococcus aureus isolate E6_22S00629-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment