Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilH   Type   Machinery gene
Locus tag   ABNR97_RS03285 Genome accession   NZ_OZ021676
Coordinates   639165..639830 (-) Length   221 a.a.
NCBI ID   WP_047918678.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae isolate SGC-23-001     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 584405..649682 639165..639830 within 0


Gene organization within MGE regions


Location: 584405..649682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABNR97_RS02895 - 584405..585058 (-) 654 WP_162855545.1 IS1595 family transposase -
  ABNR97_RS02900 purM 586056..587090 (-) 1035 WP_003692893.1 phosphoribosylformylglycinamidine cyclo-ligase -
  ABNR97_RS02905 - 587331..587519 (+) 189 WP_003689039.1 hypothetical protein -
  ABNR97_RS02910 - 587779..588768 (+) 990 WP_003689040.1 site-specific integrase -
  ABNR97_RS02915 - 589110..589589 (+) 480 WP_002241413.1 DUF4760 domain-containing protein -
  ABNR97_RS02920 - 589649..592693 (-) 3045 WP_348676487.1 tape measure protein -
  ABNR97_RS02925 - 592723..592872 (-) 150 WP_003691402.1 hypothetical protein -
  ABNR97_RS02930 - 593341..593682 (-) 342 WP_003696082.1 hypothetical protein -
  ABNR97_RS02935 - 593666..593824 (-) 159 WP_003691816.1 hypothetical protein -
  ABNR97_RS02940 - 593824..594363 (-) 540 WP_050165526.1 TIGR02594 family protein -
  ABNR97_RS02945 - 594405..594530 (-) 126 WP_255294325.1 hypothetical protein -
  ABNR97_RS02950 - 594570..594806 (+) 237 WP_003689049.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  ABNR97_RS02955 - 594806..595153 (+) 348 WP_003689051.1 type II toxin-antitoxin system PemK/MazF family toxin -
  ABNR97_RS02960 - 595509..595841 (-) 333 WP_003691408.1 hypothetical protein -
  ABNR97_RS02965 - 595842..596312 (-) 471 WP_003689057.1 hypothetical protein -
  ABNR97_RS02970 - 596383..596688 (-) 306 WP_003689058.1 hypothetical protein -
  ABNR97_RS02975 - 596800..600945 (-) 4146 WP_348676489.1 phage tail protein -
  ABNR97_RS02980 - 601185..601463 (+) 279 WP_003692877.1 helix-turn-helix domain-containing protein -
  ABNR97_RS02985 - 601491..601922 (-) 432 WP_003689064.1 NlpC/P60 family protein -
  ABNR97_RS02990 - 601924..602778 (-) 855 WP_003698614.1 DUF2163 domain-containing protein -
  ABNR97_RS02995 - 602775..603374 (-) 600 WP_003692874.1 DUF2460 domain-containing protein -
  ABNR97_RS03000 - 603374..603640 (-) 267 WP_003689070.1 hypothetical protein -
  ABNR97_RS03005 - 603652..603981 (-) 330 WP_003692871.1 hypothetical protein -
  ABNR97_RS03010 - 604042..604815 (-) 774 WP_003691416.1 hypothetical protein -
  ABNR97_RS03015 - 604841..605269 (-) 429 WP_003689076.1 hypothetical protein -
  ABNR97_RS03020 - 605266..605748 (-) 483 WP_197097348.1 HK97 gp10 family phage protein -
  ABNR97_RS03025 - 605748..606278 (-) 531 WP_003689080.1 head-tail connector protein -
  ABNR97_RS03030 - 606281..606643 (-) 363 WP_003689082.1 hypothetical protein -
  ABNR97_RS03035 - 606650..608149 (-) 1500 WP_348676490.1 hypothetical protein -
  ABNR97_RS03040 - 608190..609347 (-) 1158 WP_010360058.1 HK97 family phage prohead protease -
  ABNR97_RS03045 - 609415..611562 (-) 2148 WP_003691423.1 phage portal protein -
  ABNR97_RS03050 terL 611559..612980 (-) 1422 WP_003697216.1 phage terminase large subunit -
  ABNR97_RS03055 - 613042..613491 (-) 450 WP_003695485.1 hypothetical protein -
  ABNR97_RS03060 - 613784..614611 (-) 828 WP_348676491.1 KilA-N domain-containing protein -
  ABNR97_RS03065 - 614904..616064 (-) 1161 WP_348676492.1 type I restriction endonuclease -
  ABNR97_RS03070 - 616155..616562 (-) 408 WP_003691430.1 hypothetical protein -
  ABNR97_RS03075 - 616684..616812 (+) 129 WP_012503747.1 hypothetical protein -
  ABNR97_RS03080 - 616829..617209 (-) 381 WP_225602695.1 RusA family crossover junction endodeoxyribonuclease -
  ABNR97_RS03085 - 617200..617481 (-) 282 WP_003689109.1 hypothetical protein -
  ABNR97_RS03090 - 617509..617658 (-) 150 WP_003689110.1 hypothetical protein -
  ABNR97_RS03095 - 617835..618329 (-) 495 WP_003691434.1 DUF3310 domain-containing protein -
  ABNR97_RS03100 - 618368..618574 (-) 207 WP_154235934.1 hypothetical protein -
  ABNR97_RS03105 - 618668..620029 (-) 1362 WP_003689132.1 DnaB-like helicase C-terminal domain-containing protein -
  ABNR97_RS03110 - 620026..620529 (-) 504 WP_010360005.1 hypothetical protein -
  ABNR97_RS03115 - 621074..621211 (-) 138 WP_010359998.1 hypothetical protein -
  ABNR97_RS03120 - 621208..621435 (-) 228 WP_003698261.1 helix-turn-helix domain-containing protein -
  ABNR97_RS03125 - 621608..621796 (+) 189 WP_003691445.1 hypothetical protein -
  ABNR97_RS03130 - 621773..621928 (-) 156 WP_003689578.1 hypothetical protein -
  ABNR97_RS03135 - 622008..622244 (-) 237 WP_003687971.1 Cro/CI family transcriptional regulator -
  ABNR97_RS03140 - 622367..623029 (+) 663 WP_012503489.1 LexA family transcriptional regulator -
  ABNR97_RS03145 - 623142..623579 (+) 438 WP_003687967.1 hypothetical protein -
  ABNR97_RS03150 - 623596..624057 (+) 462 WP_003687965.1 helix-turn-helix domain-containing protein -
  ABNR97_RS03155 - 624054..624467 (+) 414 WP_003687963.1 hypothetical protein -
  ABNR97_RS03160 - 624665..624865 (+) 201 WP_047954343.1 hypothetical protein -
  ABNR97_RS03165 - 624898..625374 (+) 477 WP_002255718.1 DUF6948 domain-containing protein -
  ABNR97_RS03170 - 625371..625646 (+) 276 WP_103195391.1 hypothetical protein -
  ABNR97_RS03175 - 625787..626119 (+) 333 WP_003687946.1 hypothetical protein -
  ABNR97_RS03180 - 626272..626550 (+) 279 WP_003691529.1 NGO1622 family putative holin -
  ABNR97_RS03185 - 626547..626708 (+) 162 WP_003693867.1 hypothetical protein -
  ABNR97_RS03190 - 626777..627463 (+) 687 WP_050159915.1 phage replication initiation protein, NGO0469 family -
  ABNR97_RS03195 - 627603..627785 (+) 183 WP_003691535.1 hypothetical protein -
  ABNR97_RS03200 - 627782..628273 (+) 492 WP_003691537.1 siphovirus Gp157 family protein -
  ABNR97_RS03205 - 628325..628540 (+) 216 WP_003691538.1 hypothetical protein -
  ABNR97_RS03210 - 628651..628884 (+) 234 Protein_634 hypothetical protein -
  ABNR97_RS03215 - 629198..629881 (+) 684 WP_003687929.1 DUF2786 domain-containing protein -
  ABNR97_RS03220 - 630076..630345 (+) 270 WP_003687928.1 hypothetical protein -
  ABNR97_RS03225 - 630701..631894 (-) 1194 WP_010359935.1 phage integrase central domain-containing protein -
  ABNR97_RS03240 yaaA 632425..633204 (-) 780 WP_003706583.1 peroxide stress protein YaaA -
  ABNR97_RS03245 dapC 633515..634702 (-) 1188 WP_047949582.1 succinyldiaminopimelate transaminase -
  ABNR97_RS03250 dut 634780..635232 (-) 453 WP_103195211.1 dUTP diphosphatase -
  ABNR97_RS03255 - 635398..636105 (+) 708 Protein_641 AzlC family ABC transporter permease -
  ABNR97_RS03260 - 636102..636410 (+) 309 WP_010951048.1 AzlD family protein -
  ABNR97_RS03265 pilL 636480..636953 (-) 474 WP_025455870.1 PilX family type IV pilin Machinery gene
  ABNR97_RS03270 pilK 636955..637566 (-) 612 WP_003687918.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  ABNR97_RS03275 pilJ 637545..638525 (-) 981 WP_010951046.1 PilW family protein Machinery gene
  ABNR97_RS03280 pilV 638522..639133 (-) 612 WP_050169631.1 type IV pilus modification protein PilV Machinery gene
  ABNR97_RS03285 pilH 639165..639830 (-) 666 WP_047918678.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  ABNR97_RS03290 dnaB 639985..641391 (-) 1407 WP_047917169.1 replicative DNA helicase -
  ABNR97_RS03295 - 641555..642136 (+) 582 WP_047923823.1 superoxide dismutase -
  ABNR97_RS03300 - 642368..642877 (-) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  ABNR97_RS03305 - 643208..643540 (-) 333 WP_003687908.1 hypothetical protein -
  ABNR97_RS03310 cysT 643726..644555 (+) 830 Protein_652 sulfate ABC transporter permease subunit CysT -
  ABNR97_RS03315 cysW 644744..645565 (+) 822 WP_348676493.1 sulfate ABC transporter permease subunit CysW -
  ABNR97_RS03320 - 645561..645668 (+) 108 Protein_654 IS5/IS1182 family transposase -
  ABNR97_RS03325 - 645706..646782 (+) 1077 WP_003687905.1 sulfate/molybdate ABC transporter ATP-binding protein -
  ABNR97_RS03330 ilvA 646838..648364 (-) 1527 WP_003690890.1 threonine ammonia-lyase, biosynthetic -
  ABNR97_RS03335 - 648513..649682 (+) 1170 WP_003687902.1 D-alanyl-D-alanine carboxypeptidase family protein -

Sequence


Protein


Download         Length: 221 a.a.        Molecular weight: 24613.96 Da        Isoelectric Point: 8.6140

>NTDB_id=1162907 ABNR97_RS03285 WP_047918678.1 639165..639830(-) (pilH) [Neisseria gonorrhoeae isolate SGC-23-001]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1162907 ABNR97_RS03285 WP_047918678.1 639165..639830(-) (pilH) [Neisseria gonorrhoeae isolate SGC-23-001]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

86.878

100

0.869


Multiple sequence alignment