Detailed information NTG0116262

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: STAB902_RS03610
• Genome accession: NZ_CP007041
• Coordinates: 682270..683307 (+)
• Length: 345 a.a.
• NCBI ID: WP_010922499.1
• Uniprot ID: A0A4U9I5V9
• Organism: Streptococcus pyogenes STAB902
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 677270..688307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STAB902_RS03585 (STAB902_03750)	-	677534..678865 (+)	1332	WP_011054719.1	dipeptidase	-
STAB902_RS03590 (STAB902_03755)	arcC	678885..679835 (+)	951	WP_003051912.1	carbamate kinase	-
STAB902_RS03595 (STAB902_03760)	asnA	680148..681140 (+)	993	WP_002983817.1	aspartate--ammonia ligase	-
STAB902_RS03600 (STAB902_03765)	rsmD	681263..681802 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
STAB902_RS03605 (STAB902_03770)	coaD	681792..682283 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
STAB902_RS03610 (STAB902_03775)	sepM	682270..683307 (+)	1038	WP_010922499.1	SepM family pheromone-processing serine protease	Regulator
STAB902_RS03615 (STAB902_03780)	-	683721..684698 (+)	978	WP_011054718.1	LacI family DNA-binding transcriptional regulator	-
STAB902_RS03620 (STAB902_03785)	-	685146..685766 (+)	621	WP_002992791.1	YutD family protein	-
STAB902_RS03625 (STAB902_03790)	rlmN	685770..686849 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
STAB902_RS03630 (STAB902_03795)	-	686931..687557 (-)	627	WP_002989076.1	prepilin peptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37541.24 Da
• Isoelectric Point: 9.6692

>NTDB_id=116262 STAB902_RS03610 WP_010922499.1 682270..683307(+) (sepM) [Streptococcus pyogenes STAB902]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=116262 STAB902_RS03610 WP_010922499.1 682270..683307(+) (sepM) [Streptococcus pyogenes STAB902]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

3D structure

• AlphaFold DB: A0A4U9I5V9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.275	100	0.693