Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACKU4U_RS10200 Genome accession   NZ_OY787454
Coordinates   2059977..2061809 (+) Length   610 a.a.
NCBI ID   WP_321468332.1    Uniprot ID   -
Organism   MAG: Halarcobacter sp. isolate cd427b1f-7c2e-48dd-9f6e-f81188dbe24a     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2054977..2066809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKU4U_RS10190 (U3A33_RS10185) - 2057012..2057956 (+) 945 WP_321468328.1 HAMP domain-containing sensor histidine kinase -
  ACKU4U_RS10195 (U3A33_RS10190) - 2057953..2059677 (-) 1725 WP_321468330.1 ATP-binding protein -
  ACKU4U_RS10200 (U3A33_RS10195) uvrC 2059977..2061809 (+) 1833 WP_321468332.1 excinuclease ABC subunit UvrC Machinery gene
  ACKU4U_RS10205 (U3A33_RS10200) - 2061814..2062836 (+) 1023 WP_321468334.1 alanine racemase -
  ACKU4U_RS10210 (U3A33_RS10205) - 2062836..2063501 (+) 666 WP_321468336.1 tetratricopeptide repeat protein -
  ACKU4U_RS10215 (U3A33_RS10210) - 2063604..2064032 (+) 429 WP_321468338.1 RimK/LysX family protein -
  ACKU4U_RS10220 (U3A33_RS10215) rimK 2064033..2064974 (+) 942 WP_321468340.1 30S ribosomal protein S6--L-glutamate ligase -
  ACKU4U_RS10225 (U3A33_RS10220) - 2064978..2066030 (+) 1053 WP_321314700.1 succinylglutamate desuccinylase/aspartoacylase family protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 71367.94 Da        Isoelectric Point: 9.4208

>NTDB_id=1161951 ACKU4U_RS10200 WP_321468332.1 2059977..2061809(+) (uvrC) [MAG: Halarcobacter sp. isolate cd427b1f-7c2e-48dd-9f6e-f81188dbe24a]
MNLEEKLKQLPNEAGVYQYFDEKGKLLYIGKAKVLKNRVKSYFKFTPKLLPADKLSPRIYKMITEVKSLEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYINFNEDFPRLEITRRVLKEKNIKYFGPYSTGARDMLDSIYEIVPLVQKKSC
IKGKEACLFYQIKKCFAPCEGKISKEEYSKLVDNALNYIYNKNKLISKLTKKMEEYSNEFRFEEAMKLRDRIKTIEKSQI
QTGMDLATNENIDLFAIKIKDTKAVLVRMFFRDGKLASSNHNYIKPNKEDITIDIQEAYERAIINYYDNEIPVLPDEIII
TTELEEKDEIENFIKEKFSKKIPIITPKRGKKKEILNVALDNCNELLRLSSVKDTSSVYSQLKQLFNLDKVPNRFECFDN
SHMMGQATVGAMVTWEEKFEKGDFRHYNLESKDEYSQMRETLLRRVESFEKKPAPDMWVIDGGETLLKLAIDIRNSCGVN
LDIVAIAKEKLDFKAHRAKGSAKDIIFFENNGIVEKLDLLPSDKRLQFIQRLRDEAHRFAISFHKKQKRKEDTQISLLQI
KGIGEAKMKKLLLYFGTFENIKNSSLEELKDVLNEKDAMLIINYFKTLKG

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=1161951 ACKU4U_RS10200 WP_321468332.1 2059977..2061809(+) (uvrC) [MAG: Halarcobacter sp. isolate cd427b1f-7c2e-48dd-9f6e-f81188dbe24a]
ATGAATTTAGAAGAGAAATTAAAACAACTACCAAATGAAGCTGGAGTTTATCAATATTTTGATGAAAAAGGTAAACTTTT
ATATATAGGAAAAGCAAAAGTTTTAAAAAATAGAGTTAAATCTTATTTTAAATTTACTCCAAAACTACTACCAGCAGATA
AACTAAGTCCACGTATATATAAAATGATAACAGAGGTTAAATCATTAGAATGGATAGTTGTACCAAATGAACATGATGCT
TTAATTTTAGAAAATTCTCTTATAAAACAACTAAAACCAAAATACAATATATTACTTCGTGATGATAAAACATATCCTTA
TATTTATATAAATTTCAATGAAGACTTTCCAAGACTTGAAATTACAAGAAGAGTATTAAAAGAAAAAAATATTAAATATT
TTGGTCCCTACTCTACTGGTGCTAGAGATATGCTAGATTCTATATATGAAATAGTTCCTTTAGTACAAAAAAAATCTTGT
ATCAAAGGTAAAGAAGCTTGTCTTTTTTATCAAATAAAAAAATGTTTTGCACCATGTGAAGGGAAAATTTCAAAAGAAGA
GTATTCAAAATTAGTTGATAATGCTTTAAATTACATTTACAATAAAAATAAACTTATCTCCAAACTAACAAAAAAAATGG
AAGAATATAGCAATGAGTTTAGATTTGAAGAAGCTATGAAATTAAGAGATAGAATAAAAACTATTGAAAAATCTCAAATA
CAAACTGGTATGGATTTAGCTACAAATGAAAATATTGATCTTTTCGCAATAAAAATAAAAGATACAAAAGCGGTACTAGT
AAGAATGTTTTTTAGGGATGGGAAATTAGCTTCTAGTAATCACAACTATATAAAGCCAAATAAAGAAGATATTACTATTG
ATATACAAGAAGCTTACGAAAGAGCTATAATTAACTACTATGATAATGAAATCCCTGTTTTACCTGATGAGATTATCATT
ACAACAGAATTAGAAGAAAAAGATGAAATTGAAAACTTTATAAAAGAAAAATTCTCTAAAAAAATACCAATTATAACACC
AAAAAGAGGAAAGAAAAAAGAGATTTTAAATGTCGCATTAGATAATTGTAATGAGCTATTAAGACTCTCTTCCGTAAAAG
ATACAAGCTCAGTATATTCACAATTAAAACAATTATTCAATCTTGATAAAGTTCCTAATAGATTTGAATGCTTTGATAAT
TCACATATGATGGGACAAGCTACTGTAGGAGCTATGGTAACATGGGAAGAGAAATTTGAAAAAGGTGATTTTAGACATTA
TAATCTAGAATCAAAAGATGAATACTCTCAAATGAGAGAAACTCTATTAAGAAGAGTAGAAAGTTTTGAAAAAAAACCCG
CACCAGATATGTGGGTCATAGATGGAGGTGAAACTCTTCTTAAACTTGCAATTGATATTAGAAACTCATGTGGAGTAAAT
TTAGATATTGTAGCAATTGCAAAAGAGAAATTAGACTTTAAAGCTCATAGAGCAAAAGGTAGTGCAAAAGATATTATATT
TTTTGAAAACAATGGTATAGTTGAAAAGTTAGATTTGCTTCCTAGTGATAAACGTCTACAATTTATACAAAGATTAAGAG
ATGAGGCGCATAGATTTGCTATATCATTTCATAAAAAACAAAAAAGAAAAGAAGATACACAAATCTCTTTATTACAAATC
AAAGGTATAGGTGAAGCAAAAATGAAAAAACTTCTTTTATATTTTGGAACATTTGAAAATATAAAAAACTCTTCTTTAGA
AGAATTAAAAGATGTTCTAAACGAAAAAGATGCTATGCTTATAATAAATTATTTTAAAACTCTTAAAGGTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-541)

GIY-YIG catalytic domain (GIY-YIG)

(14-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

49.498

98.033

0.485

Multiple sequence alignment