Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   U8955_RS09895 Genome accession   NZ_OY769914
Coordinates   1971030..1973462 (-) Length   810 a.a.
NCBI ID   WP_038804752.1    Uniprot ID   A0A7T3E0I6
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1966030..1978462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS09865 (SDENT7746_09910) - 1966208..1966894 (-) 687 WP_000764012.1 YoaK family protein -
  U8955_RS09870 (SDENT7746_09915) - 1967021..1967704 (-) 684 WP_038804748.1 hypothetical protein -
  U8955_RS09875 (SDENT7746_09920) - 1967964..1968194 (+) 231 WP_038804749.1 hypothetical protein -
  U8955_RS09880 (SDENT7746_09925) - 1968266..1969039 (-) 774 WP_038804750.1 NUDIX domain-containing protein -
  U8955_RS09885 (SDENT7746_09930) pnuC 1969041..1969816 (-) 776 Protein_1888 nicotinamide riboside transporter PnuC -
  U8955_RS09890 (SDENT7746_09940) - 1969826..1970884 (-) 1059 WP_038804751.1 AAA family ATPase -
  U8955_RS09895 (SDENT7746_09945) clpC 1971030..1973462 (-) 2433 WP_038804752.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  U8955_RS09900 (SDENT7746_09950) - 1973464..1973922 (-) 459 WP_001211263.1 CtsR family transcriptional regulator -
  U8955_RS09905 (SDENT7746_09955) - 1974144..1974314 (-) 171 WP_000841982.1 helix-turn-helix domain-containing protein -
  U8955_RS09910 (SDENT7746_09960) - 1974311..1974559 (-) 249 WP_000039417.1 hypothetical protein -
  U8955_RS09915 (SDENT7746_09965) - 1974735..1975037 (-) 303 WP_000691712.1 hypothetical protein -
  U8955_RS09920 (SDENT7746_09970) - 1975053..1975781 (-) 729 WP_038804753.1 ABC transporter ATP-binding protein -
  U8955_RS09925 (SDENT7746_09975) - 1975781..1976788 (-) 1008 WP_038804754.1 ABC transporter substrate-binding protein -
  U8955_RS09930 (SDENT7746_09980) - 1976827..1977585 (-) 759 WP_068981908.1 ABC transporter permease -
  U8955_RS09935 (SDENT7746_09985) - 1977548..1977838 (-) 291 WP_000647674.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 90296.12 Da        Isoelectric Point: 6.0781

>NTDB_id=1161752 U8955_RS09895 WP_038804752.1 1971030..1973462(-) (clpC) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVTDKQNSMANMMGMPQAQSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADESDLSPADKALMDGKWKQAAQLIAKEQEVPVYKDLVTESEI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRIFEELKKAYRPEFINRIDEKVVFHSLDS
EHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASHGYNPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=1161752 U8955_RS09895 WP_038804752.1 1971030..1973462(-) (clpC) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGCCATTTTGGAGCTCGTTACCTAGA
GTCTTGGCATTTATTGATTGCCATGTCCAATCACAGTTACAGCGTGGCAGGTGCGACTTTAAACGATTATCCATACGAGA
TGGACCGTTTAGAAGAGGTTGCGTTAGAACTGACTGAAACGGACTATAGCCAGGACGAAACCTTTACGGAATTGCCTTTT
TCTCATCGTTTGGAGGTCCTATTTGCAGAAGCAGAGTATGTGGCCTCAGTGGTCCATGCAAAGGTGCTAGGGACAGAGCA
TGTATTATATGCAATCTTGCATGATGGCAATGCCTTGGCGACTCGCATCTTGGAGAGAGCAGGCTTTTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCTCTTCGTCGCAATTTAGAGGAACGTGCAGGATGGACAAGAGAAGACCTCAAGGCT
TTACGTCAACGCCATCGCACAGTAACTGACAAGCAAAATTCCATGGCCAATATGATGGGTATGCCTCAAGCTCAAAGTGG
TGGTTTAGAGGACTACACGCATGACCTGACGGAGCAAGCGCGTTCTGGCAAGTTAGAGCCAGTTATCGGTCGTGACAAGG
AAATCTCACGTATGATTCAGATTTTGAGTCGGAAGACCAAGAACAATCCGGTCTTGGTTGGAGATGCTGGTGTCGGGAAA
ACAGCTTTAGCACTTGGACTTGCTCAGCGTATTGCTAGTGGGGATGTACCTGCGGAAATGGCCAAGATGCGTGTTCTAGA
GCTTGATTTGATGAATGTTGTTGCGGGGACACGTTTCCGTGGAGATTTTGAAGAGCGCATGAACAATATCATCAAGGATA
TCGAGGAAGATGGCAAAGTAATCCTCTTTATTGATGAACTTCACACCATCATGGGTTCTGGTAGCGGTATTGATTCGACT
CTGGATGCGGCTAATATCTTGAAACCAGCCTTGGCTCGTGGAACTTTGAGAACGGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGATGCTGCCCTTTCTCGTCGGTTTGCCAAAGTGACGATTGAAGAGCCAAGTTTAGCTGACA
GTATGACTATTTTGCAAGGTTTGAAGGCGACTTATGAGAAACACCACCGTGTGCAAATCACAGATGAAGCTGTTGAAACA
GCTGTCAAGATGGCACATCGTTACTTGACCAGTCGTCACTTGCCAGACTCTGCCATTGATCTTTTGGACGAAGCGGCAGC
AACGGTGCAAAACAAATCCAAACATGTGAAAGCAGACGAATCCGACTTGAGTCCAGCTGACAAGGCATTGATGGATGGCA
AGTGGAAACAGGCAGCCCAGTTAATCGCAAAAGAACAAGAAGTCCCTGTCTATAAAGACTTGGTGACAGAATCTGAAATT
TTGACGACCTTGAGTCGCTTGTCAGGGATTCCAGTCCAAAAACTGACGCAAACAGATGCTAAGAAATACCTGAACTTGGA
AGCTGAACTACACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGTATTAGCCGAGCCATTCGCCGCAATCAGTCAG
GTATTCGCAGTCACAAACGTCCAATTGGTTCCTTTATGTTCTTAGGACCGACGGGTGTCGGGAAGACCGAATTGGCCAAG
GCTCTGGCAGAAGTTCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCAGC
TAGCCGTCTCAATGGAGCTCCTCCGGGCTATGTGGGCTACGAAGAAGGGGGGGAATTGACAGAGAAGGTCCGCAATAAAC
CTTACTCAGTGCTTCTCTTTGATGAGGTTGAAAAAGCCCACCCAGACATCTTTAATGTCCTCTTGCAAGTCTTGGACGAT
GGAGTTCTAACAGATAGCAAGGGTCGCAAGGTTGATTTTTCAAATACCATCATTATCATGACGTCAAACCTTGGTGCGAC
AGCCCTTCGTGATGACAAGACTGTCGGTTTTGGGGCCAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TTGAAGAGTTGAAAAAAGCTTATCGACCTGAGTTTATCAACCGTATTGATGAAAAGGTGGTCTTCCACAGTTTGGACAGT
GAACACATGCAGGAAATTGTCAAGATCATGGTTAAACCATTGATTGCTAGCCTAGCAGAGAAAGGCATCGACTTGAAACT
ACAAGCTTCAGCACTGAAGTTACTAGCTAGTCACGGTTACAATCCAGAAATGGGAGCCCGTCCACTTCGCAGAACACTAC
AAACCGAAGTGGAAGATAAGCTGGCAGAACTCCTTCTCAAGGGAGAACTGGTAGCAGGCAAGACCCTCAAGATTGGTGTC
AAAGCTGGTCAATTAAAATTTGATATTGCATAG

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(103-133)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(718-797)

AAA domain (Cdc48 subfamily) (AAA_2)

(540-711)

AAA lid domain (AAA_lid_9)

(371-446)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3E0I6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

96.79

100

0.968
  clpC Streptococcus pneumoniae D39

96.79

100

0.968
  clpC Streptococcus pneumoniae TIGR4

96.79

100

0.968
  clpC Streptococcus mutans UA159

67.528

100

0.678
  clpC Streptococcus thermophilus LMD-9

67.076

100

0.674
  clpC Streptococcus thermophilus LMG 18311

66.953

100

0.673
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.275

100

0.504
  clpC Bacillus subtilis subsp. subtilis str. 168

44.994

99.877

0.449
  clpE Streptococcus mutans UA159

48.71

76.543

0.373
  clpC Lactococcus lactis subsp. cremoris KW2

46.571

77.407

0.36

Multiple sequence alignment