Detailed information NTG1160526

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACI6O7_RS02815
• Genome accession: NZ_OY725152
• Coordinates: 546306..548756 (+)
• Length: 816 a.a.
• NCBI ID: WP_404379101.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain IMDO WA12L8
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 541306..553756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI6O7_RS02790 (LLWA12L8_FAMOGCFE_00565)	-	542071..542583 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
ACI6O7_RS02795 (LLWA12L8_FAMOGCFE_00566)	rpoE	542800..543363 (+)	564	WP_012897344.1	DNA-directed RNA polymerase subunit delta	-
ACI6O7_RS02800 (LLWA12L8_FAMOGCFE_00568)	mltG	543500..545151 (+)	1652	Protein_520	endolytic transglycosylase MltG	-
ACI6O7_RS02805 (LLWA12L8_FAMOGCFE_00569)	greA	545211..545684 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
ACI6O7_RS02810 (LLWA12L8_FAMOGCFE_00570)	-	545861..546316 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
ACI6O7_RS02815 (LLWA12L8_FAMOGCFE_00571)	clpC	546306..548756 (+)	2451	WP_404379101.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACI6O7_RS02820 (LLWA12L8_FAMOGCFE_00572)	hpf	548891..549448 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
ACI6O7_RS02825 (LLWA12L8_FAMOGCFE_00573)	eno	549633..550934 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
ACI6O7_RS02830 (LLWA12L8_FAMOGCFE_00574)	-	551049..551720 (-)	672	WP_010905491.1	ABC transporter ATP-binding protein	-
ACI6O7_RS02835 (LLWA12L8_FAMOGCFE_00575)	-	551723..552796 (-)	1074	WP_404379104.1	ABC transporter permease	-
ACI6O7_RS02840 (LLWA12L8_FAMOGCFE_00576)	-	552808..553377 (-)	570	WP_017864218.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90346.70 Da
• Isoelectric Point: 6.4827

>NTDB_id=1160526 ACI6O7_RS02815 WP_404379101.1 546306..548756(+) (clpC) [Lactococcus lactis strain IMDO WA12L8]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
HFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKVAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQKIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=1160526 ACI6O7_RS02815 WP_404379101.1 546306..548756(+) (clpC) [Lactococcus lactis strain IMDO WA12L8]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTAAAACGTTCAACTTTA
CATTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGGTGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAAAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACATAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTTGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• AAA lid domain (AAA_lid_9) (357-453)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.632	100	0.996
clpC	Streptococcus thermophilus LMD-9	50.421	100	0.513
clpC	Streptococcus thermophilus LMG 18311	50.301	100	0.512
clpC	Streptococcus pneumoniae Rx1	49.095	100	0.499
clpC	Streptococcus pneumoniae D39	49.095	100	0.499
clpC	Streptococcus pneumoniae TIGR4	48.975	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.623	98.284	0.498
clpC	Streptococcus mutans UA159	48.438	100	0.494
clpE	Streptococcus mutans UA159	48	79.657	0.382
clpC	Lactococcus lactis subsp. cremoris KW2	47.176	80.27	0.379
clpE	Streptococcus pneumoniae TIGR4	47.847	76.838	0.368
clpE	Streptococcus pneumoniae Rx1	47.847	76.838	0.368
clpE	Streptococcus pneumoniae D39	47.847	76.838	0.368
clpE	Streptococcus pneumoniae R6	47.847	76.838	0.368