Detailed information NTG1159914

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QOY19_RS02780
• Genome accession: NZ_OX595791
• Coordinates: 493527..494600 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae isolate MRI Z2-270
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 488527..499600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOY19_RS02750	-	489420..490484 (+)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-
QOY19_RS02755	asnA	490598..491590 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
QOY19_RS02760	-	491635..492084 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
QOY19_RS02765	rsmD	492214..492753 (+)	540	WP_001266831.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QOY19_RS02770	-	492765..493055 (+)	291	WP_000384889.1	hypothetical protein	-
QOY19_RS02775	coaD	493052..493537 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
QOY19_RS02780	sepM	493527..494600 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
QOY19_RS02785	-	494675..496007 (+)	1333	Protein_465	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
QOY19_RS02790	-	496076..496654 (+)	579	WP_283708345.1	YutD-like domain-containing protein	-
QOY19_RS02795	rlmN	496705..497811 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QOY19_RS02800	-	497811..498326 (+)	516	WP_000919803.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=1159914 QOY19_RS02780 WP_000796095.1 493527..494600(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-270]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1159914 QOY19_RS02780 WP_000796095.1 493527..494600(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-270]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658