Detailed information NTG1159649

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: QOR57_RS02840
• Genome accession: NZ_OX461088
• Coordinates: 507142..509403 (-)
• Length: 753 a.a.
• NCBI ID: WP_017647074.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-338
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 502142..514403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR57_RS02820	-	502171..502941 (+)	771	WP_283571976.1	DivIVA domain-containing protein	-
QOR57_RS02825	ileS	503226..506018 (+)	2793	WP_000768156.1	isoleucine--tRNA ligase	-
QOR57_RS02830	-	506135..506437 (-)	303	WP_001237035.1	DUF1827 family protein	-
QOR57_RS02835	-	506501..506956 (-)	456	WP_000184290.1	NUDIX hydrolase	-
QOR57_RS02840	clpE	507142..509403 (-)	2262	WP_017647074.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QOR57_RS02845	-	509701..509931 (+)	231	WP_000443582.1	DUF1797 family protein	-
QOR57_RS02850	-	510072..510764 (+)	693	WP_001011647.1	amino acid ABC transporter permease	-
QOR57_RS02855	-	510757..511491 (+)	735	WP_000230128.1	amino acid ABC transporter ATP-binding protein	-
QOR57_RS02860	-	511778..513472 (+)	1695	WP_017647075.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83778.99 Da
• Isoelectric Point: 5.2771

>NTDB_id=1159649 QOR57_RS02840 WP_017647074.1 507142..509403(-) (clpE) [Streptococcus agalactiae isolate MRI Z2-338]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGINPFFDDFFGDLNNFRAFNGQDL
PNTPPTQSGGNRGGGNGNGRNNNRNQTATPPQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEMDQRLIEAENLKAQATREEDYERAAYFRDQIAK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVIKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEASVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESAKG

Nucleotide

• Length: 2262 bp

>NTDB_id=1159649 QOR57_RS02840 WP_017647074.1 507142..509403(-) (clpE) [Streptococcus agalactiae isolate MRI Z2-338]
ATGCTCTGTCAAAACTGCAAACTAAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCATCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAACACTCCTCCTACACAATCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTCCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGTGAACCCGGCGTAGGGAAAACTGCTGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCTACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGTATGCAACCTGTAAAAGTCG
ATGAGCCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCACGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAAGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATGGATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGCGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTGCAAAA
TATAAAGAAATGCAACAACAAAAAGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AACATGTGATCGGCCAGGATGACGCTGTCATTAAGATTGCAAAAGCTATTCGTCGTAATCGTGTTGGTCTTGGTAGCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGTGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGATATGTCAGAGTACATGGAAAAGCATGCTGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAATTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCTGATGTCATGCATATGTTCTTGCAGGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
GCGTTGGCTTTGGTGCCTCACGAGAAGGTAGGACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGATAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCAAAAATGGGAGCACGTCCATTACGTCGTACCATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAGGAAAGTGCAAAAGGTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-727)

• AAA lid domain (AAA_lid_9) (297-394)

• ATPase family associated with various cellular activities (AAA) (AAA) (159-276)

• AAA domain (Cdc48 subfamily) (AAA_2) (482-645)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.411	100	0.855
clpE	Streptococcus pneumoniae Rx1	85.447	99.469	0.85
clpE	Streptococcus pneumoniae D39	85.447	99.469	0.85
clpE	Streptococcus pneumoniae R6	85.447	99.469	0.85
clpE	Streptococcus pneumoniae TIGR4	85.314	99.469	0.849
clpC	Lactococcus lactis subsp. cremoris KW2	74.601	99.867	0.745
clpC	Bacillus subtilis subsp. subtilis str. 168	51.18	90.04	0.461
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.528	83.267	0.396
clpC	Streptococcus pneumoniae Rx1	47.003	84.197	0.396
clpC	Streptococcus pneumoniae D39	47.003	84.197	0.396
clpC	Streptococcus pneumoniae TIGR4	46.845	84.197	0.394
clpC	Streptococcus mutans UA159	47.03	82.736	0.389
clpC	Streptococcus thermophilus LMD-9	46.117	83.798	0.386
clpC	Streptococcus thermophilus LMG 18311	45.8	83.798	0.384