Detailed information NTG1159304

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QOR61_RS02935
• Genome accession: NZ_OX460960
• Coordinates: 523066..524139 (+)
• Length: 357 a.a.
• NCBI ID: WP_000790650.1
• Uniprot ID: A0A0H1YUL6
• Organism: Streptococcus agalactiae isolate MRI Z2-299
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 518066..529139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR61_RS02905	-	518957..520021 (+)	1065	WP_000021310.1	MmcQ/YjbR family DNA-binding protein	-
QOR61_RS02910	asnA	520136..521128 (+)	993	WP_000748010.1	aspartate--ammonia ligase	-
QOR61_RS02915	-	521173..521622 (-)	450	WP_000592264.1	bacteriocin transport accessory protein	-
QOR61_RS02920	rsmD	521753..522292 (+)	540	WP_001872952.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QOR61_RS02925	-	522304..522594 (+)	291	WP_000384889.1	hypothetical protein	-
QOR61_RS02930	coaD	522591..523076 (+)	486	WP_000161889.1	pantetheine-phosphate adenylyltransferase	-
QOR61_RS02935	sepM	523066..524139 (+)	1074	WP_000790650.1	SepM family pheromone-processing serine protease	Regulator
QOR61_RS02940	-	524214..525548 (+)	1335	WP_000137519.1	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
QOR61_RS02945	-	525617..526195 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
QOR61_RS02950	rlmN	526246..527352 (+)	1107	WP_001124996.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QOR61_RS02955	-	527352..527867 (+)	516	WP_000919737.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39145.29 Da
• Isoelectric Point: 10.4045

>NTDB_id=1159304 QOR61_RS02935 WP_000790650.1 523066..524139(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-299]
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKQGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1159304 QOR61_RS02935 WP_000790650.1 523066..524139(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-299]
GTGAAGAATAAAGATCCAAAAAGAAAACATAAAAGTTTGCTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTGGTGAGGCTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATCATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTAGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGCACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAACAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (241-307)

3D structure

• AlphaFold DB: A0A0H1YUL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658