Detailed information NTG1158977

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QOR45_RS03025
• Genome accession: NZ_OX460935
• Coordinates: 532062..533135 (+)
• Length: 357 a.a.
• NCBI ID: WP_000790653.1
• Uniprot ID: A0A7Z7K6V3
• Organism: Streptococcus agalactiae isolate MRI Z2-286
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 527062..538135

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR45_RS02995	-	527953..529017 (+)	1065	WP_000021298.1	MmcQ/YjbR family DNA-binding protein	-
QOR45_RS03000	asnA	529132..530124 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
QOR45_RS03005	-	530169..530618 (-)	450	WP_283572091.1	bacteriocin transport accessory protein	-
QOR45_RS03010	rsmD	530749..531288 (+)	540	WP_032459123.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QOR45_RS03015	-	531300..531590 (+)	291	WP_000384889.1	hypothetical protein	-
QOR45_RS03020	coaD	531587..532072 (+)	486	WP_000161887.1	pantetheine-phosphate adenylyltransferase	-
QOR45_RS03025	sepM	532062..533135 (+)	1074	WP_000790653.1	SepM family pheromone-processing serine protease	Regulator
QOR45_RS03030	-	533210..534544 (+)	1335	WP_000137514.1	bifunctional metallophosphatase/5'-nucleotidase	-
QOR45_RS03035	-	534613..535191 (+)	579	WP_001224503.1	YutD-like domain-containing protein	-
QOR45_RS03040	rlmN	535242..536348 (+)	1107	WP_001124994.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QOR45_RS03045	-	536348..536863 (+)	516	WP_000919809.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39176.40 Da
• Isoelectric Point: 10.4619

>NTDB_id=1158977 QOR45_RS03025 WP_000790653.1 532062..533135(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-286]
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESVYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSNVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGFKVVSAAKKGMDIFFVPNNPIDKNAKKGKIKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1158977 QOR45_RS03025 WP_000790653.1 532062..533135(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-286]
GTGAAGAATAAAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTGGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTTAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCGTCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGTAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATCATCTAATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTTAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAATAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (241-307)

3D structure

• AlphaFold DB: A0A7Z7K6V3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.732	94.958	0.653