Detailed information NTG1158923

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: QOR46_RS02935
• Genome accession: NZ_OX460934
• Coordinates: 530583..532844 (-)
• Length: 753 a.a.
• NCBI ID: WP_141444603.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-335
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 525583..537844

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR46_RS02915	-	525612..526382 (+)	771	WP_001131467.1	DivIVA domain-containing protein	-
QOR46_RS02920	ileS	526667..529459 (+)	2793	WP_000768163.1	isoleucine--tRNA ligase	-
QOR46_RS02925	-	529576..529878 (-)	303	WP_001237035.1	DUF1827 family protein	-
QOR46_RS02930	-	529942..530397 (-)	456	WP_000184292.1	NUDIX hydrolase	-
QOR46_RS02935	clpE	530583..532844 (-)	2262	WP_141444603.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QOR46_RS02940	-	533142..533372 (+)	231	WP_000443582.1	DUF1797 family protein	-
QOR46_RS02945	-	533515..534207 (+)	693	WP_001011647.1	amino acid ABC transporter permease	-
QOR46_RS02950	-	534200..534934 (+)	735	WP_000230130.1	amino acid ABC transporter ATP-binding protein	-
QOR46_RS02955	-	535221..536915 (+)	1695	WP_001106845.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83765.93 Da
• Isoelectric Point: 5.3467

>NTDB_id=1158923 QOR46_RS02935 WP_141444603.1 530583..532844(-) (clpE) [Streptococcus agalactiae isolate MRI Z2-335]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGINPFFDDFFGDLNNFRAFNGQDL
PNTPPTQSGGNRGGGNGNGRNNNRNQTATPSQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEINQRLIEAENLKAQATREEDYERAAYFRDQIAK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVVKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEASVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESTKG

Nucleotide

• Length: 2262 bp

>NTDB_id=1158923 QOR46_RS02935 WP_141444603.1 530583..532844(-) (clpE) [Streptococcus agalactiae isolate MRI Z2-335]
ATGCTCTGTCAAAACTGCAAACTAAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCATCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAACACTCCTCCTACACAATCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTTCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGCGAACCCGGCGTTGGGAAAACTGCCGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCTACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGTATGCAACCTGTAAAAGTCG
ATGAGCCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCATGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAGGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATTAATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGCGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTGCAAAA
TATAAAGAAATGCAACAACAAAAGGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AACATGTGATCGGCCAGGATGACGCTGTCGTTAAGATTGCAAAAGCTATTCGTCGTAATCGAGTTGGTCTTGGTAGCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGCGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGATATGTCAGAGTACATGGAAAAGCATGCTGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAATTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCTGATGTCATGCATATGTTCTTGCAGGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
GCGTTGGCTTTGGTGCCTCACGAGAAGGTAGAACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGATAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCCAAAATGGGAGCACGTCCATTACGTCGTACCATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAAGAAAGTACAAAAGGTTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (159-276)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-727)

• AAA domain (Cdc48 subfamily) (AAA_2) (482-645)

• AAA lid domain (AAA_lid_9) (297-394)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.544	100	0.857
clpE	Streptococcus pneumoniae Rx1	85.581	99.469	0.851
clpE	Streptococcus pneumoniae D39	85.581	99.469	0.851
clpE	Streptococcus pneumoniae R6	85.581	99.469	0.851
clpE	Streptococcus pneumoniae TIGR4	85.447	99.469	0.85
clpC	Lactococcus lactis subsp. cremoris KW2	75	99.867	0.749
clpC	Bacillus subtilis subsp. subtilis str. 168	51.327	90.04	0.462
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.368	83.267	0.394
clpC	Streptococcus pneumoniae Rx1	46.082	84.728	0.39
clpC	Streptococcus pneumoniae D39	46.082	84.728	0.39
clpC	Streptococcus pneumoniae TIGR4	45.925	84.728	0.389
clpC	Streptococcus mutans UA159	47.097	82.337	0.388
clpC	Streptococcus thermophilus LMD-9	46.117	83.798	0.386
clpC	Streptococcus thermophilus LMG 18311	45.8	83.798	0.384