Detailed information NTG1158922

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QOR46_RS02770
• Genome accession: NZ_OX460934
• Coordinates: 497668..498741 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae isolate MRI Z2-335
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 492668..503741

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR46_RS02740	-	493561..494625 (+)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-
QOR46_RS02745	asnA	494739..495731 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
QOR46_RS02750	-	495776..496225 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
QOR46_RS02755	rsmD	496355..496894 (+)	540	WP_001266831.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QOR46_RS02760	-	496906..497196 (+)	291	WP_000384889.1	hypothetical protein	-
QOR46_RS02765	coaD	497193..497678 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
QOR46_RS02770	sepM	497668..498741 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
QOR46_RS02775	-	498816..500148 (+)	1333	Protein_461	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
QOR46_RS02780	-	500217..500795 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
QOR46_RS02785	rlmN	500846..501952 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QOR46_RS02790	-	501952..502467 (+)	516	WP_000919803.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=1158922 QOR46_RS02770 WP_000796095.1 497668..498741(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-335]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1158922 QOR46_RS02770 WP_000796095.1 497668..498741(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-335]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658