Detailed information NTG1158869

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QOR44_RS02530
• Genome accession: NZ_OX460931
• Coordinates: 448164..449237 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae isolate MRI Z2-174
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 443164..454237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR44_RS02500	-	444057..445121 (+)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-
QOR44_RS02505	asnA	445235..446227 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
QOR44_RS02510	-	446272..446721 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
QOR44_RS02515	rsmD	446851..447390 (+)	540	WP_001266831.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QOR44_RS02520	-	447402..447692 (+)	291	WP_000384889.1	hypothetical protein	-
QOR44_RS02525	coaD	447689..448174 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
QOR44_RS02530	sepM	448164..449237 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
QOR44_RS02535	-	449312..450644 (+)	1333	Protein_414	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
QOR44_RS02540	-	450713..451291 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
QOR44_RS02545	rlmN	451342..452448 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QOR44_RS02550	-	452448..452963 (+)	516	WP_000919803.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=1158869 QOR44_RS02530 WP_000796095.1 448164..449237(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-174]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1158869 QOR44_RS02530 WP_000796095.1 448164..449237(+) (sepM) [Streptococcus agalactiae isolate MRI Z2-174]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658