Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   A436_RS12070 Genome accession   NZ_CP007017
Coordinates   2358261..2360066 (-) Length   601 a.a.
NCBI ID   WP_003722312.1    Uniprot ID   A0A402X5H7
Organism   Listeria monocytogenes serotype 1/2a str. 10-1046     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2353261..2365066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A436_RS12050 (A436_2359) isdE 2354185..2355057 (-) 873 WP_003722308.1 heme ABC transporter substrate-binding protein IsdE -
  A436_RS12055 (A436_2360) hbp2 2355144..2356853 (-) 1710 WP_003722309.1 hemin/hemoglobin-binding protein Hbp2 -
  A436_RS12060 (A436_2361) isdC 2356868..2357491 (-) 624 WP_003731900.1 heme uptake protein IsdC -
  A436_RS12065 (A436_2362) - 2357702..2357962 (-) 261 WP_003722311.1 DUF3116 family protein -
  A436_RS12070 (A436_2363) pepF 2358261..2360066 (-) 1806 WP_003722312.1 oligoendopeptidase F Regulator
  A436_RS12075 (A436_2364) - 2360139..2361254 (-) 1116 WP_003734058.1 competence protein CoiA -
  A436_RS12080 (A436_2365) mecA 2361380..2362033 (-) 654 WP_003722314.1 adaptor protein MecA -
  A436_RS12085 (A436_2366) spxA 2362265..2362660 (-) 396 WP_003720569.1 transcriptional regulator SpxA -
  A436_RS12090 (A436_2367) - 2362979..2363947 (-) 969 WP_003722315.1 ABC transporter ATP-binding protein -
  A436_RS12095 (A436_2368) - 2363944..2365020 (-) 1077 WP_012951901.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 68615.62 Da        Isoelectric Point: 4.5492

>NTDB_id=115837 A436_RS12070 WP_003722312.1 2358261..2360066(-) (pepF) [Listeria monocytogenes serotype 1/2a str. 10-1046]
MSKTNALPLREEVPENLTWDLTTIYPNDEAWEQAFTDLQKITEESEQFKGRLSESSQTLYEALQFRDKAYDLISNLYVYA
HLKMDQDTANAKYQGLHSRAGSLVTKLMSALSYYDPEILAMDENVLKQFLDENKDLQLYDHLLEELNLSRPYILSEKEEA
LLANAGEVLGSSSNTFNTLNNADMKFPTIKDENGEDIEITHGRFGKLLESNDPRVRRDAFHGVYSVYEGLKNTLASTLNG
QVKKSNFYASTRGYTSAREAALSGNHIPETVYDSLLKSVNANASLLHRYVKLRKELLGLEELHMYDLYTPLSDDVNLEFT
YEEAKELVLEALKPLGDEYQAILKEAFDSRWIDVMENKGKRSGAYSSGSYSTNPYILLNWQDNINNVYTLAHELGHSVHS
YYTRKNQPFVYGDYSIFLAEVASTTNENLLTDYLLKKYDDPKVRAYLLNHYLDGFKGTVFRQTQFAEFEHAIHQADQQGV
ALTADFLTETYFDINKKYYGEAMVYDAEIGYEWSRIPHFYMNYYVFQYATGFSAASALSAKILTEGQDAVTAYIDFLKAG
SSDYPIDVLKKAGVDMATPNPVDDALKVFEQRLDELEELVK

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=115837 A436_RS12070 WP_003722312.1 2358261..2360066(-) (pepF) [Listeria monocytogenes serotype 1/2a str. 10-1046]
TTGAGTAAAACAAATGCATTACCTTTAAGAGAAGAAGTACCAGAAAATCTAACTTGGGATTTAACTACGATATATCCAAA
TGATGAAGCTTGGGAACAAGCATTTACAGATTTGCAAAAAATCACAGAAGAAAGCGAGCAATTTAAAGGTCGTTTATCGG
AAAGTAGCCAAACACTTTATGAAGCACTTCAATTTCGAGATAAAGCATATGATTTGATTAGTAACTTATATGTATATGCT
CATTTGAAAATGGACCAAGATACAGCTAATGCGAAATATCAAGGTTTACATAGTCGTGCAGGAAGCCTAGTTACAAAGCT
AATGTCTGCACTCTCTTACTATGACCCAGAAATTTTAGCTATGGATGAAAATGTTCTAAAACAATTTTTAGATGAGAATA
AAGATTTACAATTATATGATCATTTGTTGGAAGAGTTAAATTTAAGTCGACCTTATATTTTGAGTGAGAAGGAAGAGGCT
TTACTAGCTAATGCAGGTGAAGTGCTTGGAAGTTCGTCCAATACTTTTAATACCTTGAATAATGCTGATATGAAGTTTCC
AACTATTAAAGATGAAAATGGGGAAGATATCGAAATTACTCATGGCCGTTTTGGGAAATTGTTAGAAAGTAATGATCCAC
GAGTGCGTCGTGATGCATTTCATGGTGTGTATTCAGTTTATGAAGGATTAAAAAACACATTAGCATCTACTTTAAATGGA
CAAGTGAAAAAATCTAATTTTTATGCTTCTACGCGAGGGTATACATCGGCTCGTGAAGCGGCTCTCTCTGGTAATCATAT
TCCTGAAACAGTATATGACTCATTGTTGAAATCAGTGAATGCTAATGCAAGTTTGCTTCATCGTTATGTGAAGTTACGTA
AGGAATTACTTGGCTTAGAAGAATTGCATATGTATGACCTTTATACGCCACTTTCTGATGATGTTAATTTGGAGTTCACT
TATGAGGAAGCAAAAGAACTCGTGCTTGAGGCGCTGAAACCACTTGGTGATGAATATCAAGCGATTTTAAAAGAGGCATT
TGATAGTCGTTGGATTGATGTGATGGAAAATAAAGGGAAACGTAGTGGAGCCTATTCTTCTGGTTCATATAGTACGAATC
CTTATATTTTACTCAATTGGCAAGATAATATTAATAATGTTTACACGCTTGCACATGAATTAGGACATAGTGTGCATAGT
TATTATACAAGAAAAAATCAACCATTTGTTTATGGTGATTATTCGATTTTCTTAGCGGAGGTTGCTTCGACTACGAATGA
AAATTTACTAACTGATTATCTGCTTAAGAAATATGATGATCCAAAAGTTCGTGCATACTTGTTGAATCACTATTTGGATG
GATTCAAGGGTACTGTATTCCGTCAAACGCAATTTGCTGAATTTGAACATGCCATTCATCAAGCGGATCAACAAGGAGTG
GCTTTGACTGCGGATTTCTTGACGGAAACATATTTTGATATTAACAAGAAATATTACGGAGAAGCGATGGTTTATGATGC
TGAAATTGGTTATGAATGGTCTCGGATTCCGCATTTTTATATGAATTATTATGTGTTCCAATATGCGACTGGTTTTTCAG
CAGCATCTGCATTAAGTGCGAAAATTTTAACAGAAGGTCAAGACGCTGTAACAGCCTATATTGATTTCTTGAAAGCAGGA
AGTTCGGATTATCCTATCGATGTGTTGAAAAAAGCAGGTGTCGATATGGCGACCCCTAATCCCGTAGATGATGCATTAAA
GGTATTTGAACAAAGATTGGATGAATTGGAAGAGCTGGTTAAATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-586)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A402X5H7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.351

98.502

0.506

Multiple sequence alignment