Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KJP47_RS06290 Genome accession   NZ_OX419577
Coordinates   1223110..1223766 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis isolate NRS6120     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1218110..1228766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJP47_RS06260 (NRS6120_06620) oppF 1218573..1219490 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KJP47_RS06265 (NRS6120_06625) yjbB 1219598..1220815 (+) 1218 WP_213383532.1 MFS transporter -
  KJP47_RS06270 (NRS6120_06630) yjbC 1220980..1221558 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  KJP47_RS06275 (NRS6120_06635) spx 1221739..1222134 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  KJP47_RS06280 (NRS6120_06640) yjbE 1222177..1222833 (-) 657 WP_213383520.1 TerC family protein -
  KJP47_RS06285 - 1223003..1223143 (+) 141 WP_119122854.1 hypothetical protein -
  KJP47_RS06290 (NRS6120_06645) mecA 1223110..1223766 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  KJP47_RS06295 - 1223761..1223883 (-) 123 WP_003245684.1 hypothetical protein -
  KJP47_RS06300 (NRS6120_06650) coiA 1223927..1225078 (+) 1152 WP_213383521.1 competence protein CoiA Machinery gene
  KJP47_RS06305 (NRS6120_06655) pepF 1225308..1227137 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  KJP47_RS06310 (NRS6120_06660) - 1227175..1227342 (-) 168 WP_003244944.1 hypothetical protein -
  KJP47_RS06315 (NRS6120_06675) spxH 1227656..1228555 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=1157733 KJP47_RS06290 WP_014479448.1 1223110..1223766(+) (mecA) [Bacillus subtilis isolate NRS6120]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1157733 KJP47_RS06290 WP_014479448.1 1223110..1223766(+) (mecA) [Bacillus subtilis isolate NRS6120]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment