Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SMUFR_RS06420 Genome accession   NZ_CP007016
Coordinates   1326727..1327620 (+) Length   297 a.a.
NCBI ID   WP_002262721.1    Uniprot ID   A0A090B2L0
Organism   Streptococcus mutans UA159-FR     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1321727..1332620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUFR_RS10945 - 1323690..1323818 (-) 129 WP_002262718.1 hypothetical protein -
  SMUFR_RS10870 - 1323853..1324083 (-) 231 WP_002282891.1 hypothetical protein -
  SMUFR_RS06410 (SMUFR_1211) gbpC 1324213..1325964 (-) 1752 WP_002262719.1 glucan-binding protein GbpC -
  SMUFR_RS06415 (SMUFR_1212) - 1326127..1326412 (-) 286 Protein_1241 helix-turn-helix transcriptional regulator -
  SMUFR_RS06420 (SMUFR_1213) irvR 1326727..1327620 (+) 894 WP_002262721.1 LexA family transcriptional regulator IrvR Regulator
  SMUFR_RS06425 (SMUFR_1214) - 1328289..1328666 (-) 378 WP_002263544.1 type II toxin-antitoxin system HicB family antitoxin -
  SMUFR_RS06430 (SMUFR_1215) - 1328684..1328875 (-) 192 WP_002263545.1 type II toxin-antitoxin system HicA family toxin -
  SMUFR_RS06435 (SMUFR_1216) csn2 1328972..1329634 (-) 663 WP_002263546.1 type II-A CRISPR-associated protein Csn2 -
  SMUFR_RS06440 (SMUFR_1217) cas2 1329624..1329968 (-) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  SMUFR_RS06445 (SMUFR_1218) cas1 1329965..1330831 (-) 867 WP_002352326.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33651.40 Da        Isoelectric Point: 6.7038

>NTDB_id=115772 SMUFR_RS06420 WP_002262721.1 1326727..1327620(+) (irvR) [Streptococcus mutans UA159-FR]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTEDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALIVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=115772 SMUFR_RS06420 WP_002262721.1 1326727..1327620(+) (irvR) [Streptococcus mutans UA159-FR]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCTACTATTCTTAACATTCCTACAAGTAGTCTTAACGAATATGTTAAGGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTTTACAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAGATGAAACAGCAAGCTTGTCTGCCAGTGATGAAACGACTGAGGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTATTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A090B2L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

100

100

1

Multiple sequence alignment