Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KJP57_RS06560 Genome accession   NZ_OX419573
Coordinates   1249379..1250035 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis isolate NRS6085     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1244379..1255035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJP57_RS06530 (NRS6085_06530) oppF 1244844..1245761 (+) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KJP57_RS06535 (NRS6085_06535) yjbB 1245867..1247084 (+) 1218 WP_128737746.1 MFS transporter -
  KJP57_RS06540 (NRS6085_06540) yjbC 1247249..1247827 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  KJP57_RS06545 (NRS6085_06545) spx 1248008..1248403 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  KJP57_RS06550 (NRS6085_06550) yjbE 1248446..1249102 (-) 657 WP_003232944.1 TerC family protein -
  KJP57_RS06555 - 1249272..1249412 (+) 141 WP_119122854.1 hypothetical protein -
  KJP57_RS06560 (NRS6085_06555) mecA 1249379..1250035 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  KJP57_RS06565 - 1250030..1250152 (-) 123 WP_003245684.1 hypothetical protein -
  KJP57_RS06570 (NRS6085_06560) coiA 1250196..1251347 (+) 1152 WP_128737747.1 competence protein CoiA Machinery gene
  KJP57_RS06575 (NRS6085_06565) pepF 1251577..1253406 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  KJP57_RS06580 (NRS6085_06570) - 1253444..1253611 (-) 168 WP_003244944.1 hypothetical protein -
  KJP57_RS06585 (NRS6085_06585) spxH 1253925..1254824 (-) 900 WP_128737748.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=1157486 KJP57_RS06560 WP_003245194.1 1249379..1250035(+) (mecA) [Bacillus subtilis isolate NRS6085]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1157486 KJP57_RS06560 WP_003245194.1 1249379..1250035(+) (mecA) [Bacillus subtilis isolate NRS6085]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment