Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KJP69_RS06225 Genome accession   NZ_OX419550
Coordinates   1207247..1207903 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis isolate NRS6187     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1202247..1212903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJP69_RS06195 (NRS6187_06145) oppF 1202712..1203629 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KJP69_RS06200 (NRS6187_06150) yjbB 1203736..1204953 (+) 1218 WP_010886478.1 MFS transporter -
  KJP69_RS06205 (NRS6187_06155) yjbC 1205117..1205695 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  KJP69_RS06210 (NRS6187_06160) spx 1205876..1206271 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  KJP69_RS06215 (NRS6187_06165) yjbE 1206314..1206970 (-) 657 WP_003232944.1 TerC family protein -
  KJP69_RS06220 - 1207140..1207280 (+) 141 WP_119122854.1 hypothetical protein -
  KJP69_RS06225 (NRS6187_06170) mecA 1207247..1207903 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  KJP69_RS06230 - 1207898..1208020 (-) 123 WP_128473814.1 hypothetical protein -
  KJP69_RS06235 (NRS6187_06175) coiA 1208064..1209215 (+) 1152 WP_029317613.1 competence protein CoiA Machinery gene
  KJP69_RS06240 (NRS6187_06180) pepF 1209445..1211274 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  KJP69_RS06245 (NRS6187_06185) - 1211312..1211479 (-) 168 WP_003244944.1 hypothetical protein -
  KJP69_RS06250 (NRS6187_06195) spxH 1211794..1212693 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=1156338 KJP69_RS06225 WP_003232942.1 1207247..1207903(+) (mecA) [Bacillus subtilis isolate NRS6187]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1156338 KJP69_RS06225 WP_003232942.1 1207247..1207903(+) (mecA) [Bacillus subtilis isolate NRS6187]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAGATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment