Detailed information NTG1155563

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QNH68_RS01530
• Genome accession: NZ_OX352944
• Coordinates: 324517..325566 (+)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis isolate 861160_LM_H
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 319517..330566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH68_RS01495	-	319819..320757 (+)	939	WP_232049074.1	histidine kinase	-
QNH68_RS01500	-	320910..321512 (+)	603	WP_024405571.1	response regulator transcription factor	-
QNH68_RS01505	-	321820..322038 (+)	219	WP_024405570.1	YqgQ family protein	-
QNH68_RS01510	-	322038..322424 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
QNH68_RS01515	-	322481..323203 (+)	723	WP_024405569.1	hypothetical protein	-
QNH68_RS01520	rsmD	323513..324052 (+)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QNH68_RS01525	coaD	324042..324530 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
QNH68_RS01530	sepM	324517..325566 (+)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
QNH68_RS01535	-	325754..326395 (+)	642	WP_024382386.1	YutD-like domain-containing protein	-
QNH68_RS01540	rlmN	326404..327516 (+)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QNH68_RS01545	-	327513..328040 (+)	528	WP_012027591.1	VanZ family protein	-
QNH68_RS01550	nadE	329336..330160 (-)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=1155563 QNH68_RS01530 WP_012775295.1 324517..325566(+) (sepM) [Streptococcus suis isolate 861160_LM_H]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1155563 QNH68_RS01530 WP_012775295.1 324517..325566(+) (sepM) [Streptococcus suis isolate 861160_LM_H]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605