Detailed information NTG1155496

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QNH71_RS00410
• Genome accession: NZ_OX352941
• Coordinates: 76970..78019 (+)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis isolate 861160_WT
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 71970..83019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH71_RS00375	-	72272..73210 (+)	939	WP_232049074.1	histidine kinase	-
QNH71_RS00380	-	73363..73965 (+)	603	WP_024405571.1	response regulator transcription factor	-
QNH71_RS00385	-	74273..74491 (+)	219	WP_024405570.1	YqgQ family protein	-
QNH71_RS00390	-	74491..74877 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
QNH71_RS00395	-	74934..75656 (+)	723	WP_024405569.1	hypothetical protein	-
QNH71_RS00400	rsmD	75966..76505 (+)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QNH71_RS00405	coaD	76495..76983 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
QNH71_RS00410	sepM	76970..78019 (+)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
QNH71_RS00415	-	78207..78848 (+)	642	WP_024382386.1	YutD-like domain-containing protein	-
QNH71_RS00420	rlmN	78857..79969 (+)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QNH71_RS00425	-	79966..80493 (+)	528	WP_012027591.1	VanZ family protein	-
QNH71_RS00430	nadE	81789..82613 (-)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=1155496 QNH71_RS00410 WP_012775295.1 76970..78019(+) (sepM) [Streptococcus suis isolate 861160_WT]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1155496 QNH71_RS00410 WP_012775295.1 76970..78019(+) (sepM) [Streptococcus suis isolate 861160_WT]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605