Detailed information NTG1155459

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QNH65_RS05650
• Genome accession: NZ_OX352940
• Coordinates: 1157853..1158902 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis isolate 861160_LM_A
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1152853..1163902

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH65_RS05630	nadE	1153259..1154083 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
QNH65_RS05635	-	1155379..1155906 (-)	528	WP_012027591.1	VanZ family protein	-
QNH65_RS05640	rlmN	1155903..1157015 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QNH65_RS05645	-	1157024..1157665 (-)	642	WP_024382386.1	YutD-like domain-containing protein	-
QNH65_RS05650	sepM	1157853..1158902 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
QNH65_RS05655	coaD	1158889..1159377 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
QNH65_RS05660	rsmD	1159367..1159906 (-)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QNH65_RS05665	-	1160216..1160938 (-)	723	WP_024405569.1	hypothetical protein	-
QNH65_RS05670	-	1160995..1161381 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
QNH65_RS05675	-	1161381..1161599 (-)	219	WP_024405570.1	YqgQ family protein	-
QNH65_RS05680	-	1161907..1162509 (-)	603	WP_024405571.1	response regulator transcription factor	-
QNH65_RS05685	-	1162662..1163600 (-)	939	WP_232049074.1	histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=1155459 QNH65_RS05650 WP_012775295.1 1157853..1158902(-) (sepM) [Streptococcus suis isolate 861160_LM_A]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1155459 QNH65_RS05650 WP_012775295.1 1157853..1158902(-) (sepM) [Streptococcus suis isolate 861160_LM_A]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605