Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   QML63_RS10350 Genome accession   NZ_OX346406
Coordinates   2086643..2088460 (-) Length   605 a.a.
NCBI ID   WP_282013509.1    Uniprot ID   A0AAW9K189
Organism   Enterococcus cecorum isolate CIRMBP-1212     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2081643..2093460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML63_RS10325 (CIRMBP1212_02058) - 2081644..2082597 (-) 954 WP_047242628.1 metal ABC transporter substrate-binding protein -
  QML63_RS10330 (CIRMBP1212_02059) - 2083233..2084075 (+) 843 WP_282013508.1 Rgg/GadR/MutR family transcriptional regulator -
  QML63_RS10335 (CIRMBP1212_02060) - 2084227..2085114 (+) 888 WP_047242626.1 ABC transporter ATP-binding protein -
  QML63_RS10340 (CIRMBP1212_02061) - 2085111..2085845 (+) 735 WP_016250664.1 ABC transporter permease -
  QML63_RS10345 (CIRMBP1212_02062) - 2085838..2086398 (+) 561 WP_047242625.1 hypothetical protein -
  QML63_RS10350 (CIRMBP1212_02063) pepF 2086643..2088460 (-) 1818 WP_282013509.1 oligoendopeptidase F Regulator
  QML63_RS10355 (CIRMBP1212_02064) - 2088502..2089500 (-) 999 WP_282013510.1 competence protein CoiA family protein -
  QML63_RS10360 (CIRMBP1212_02065) ispE 2089578..2090429 (-) 852 WP_282013511.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
  QML63_RS10365 (CIRMBP1212_02066) - 2090715..2092286 (-) 1572 WP_282013512.1 ABC transporter ATP-binding protein -
  QML63_RS10370 (CIRMBP1212_02067) - 2092376..2093248 (-) 873 WP_060470648.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 605 a.a.        Molecular weight: 69295.72 Da        Isoelectric Point: 4.7048

>NTDB_id=1155142 QML63_RS10350 WP_282013509.1 2086643..2088460(-) (pepF) [Enterococcus cecorum isolate CIRMBP-1212]
MSETKQLPLRSEVPEELTWDLSVIFKDDAAFEEAFAALNDRLAEVGNYQGTLANGAKAFLAALEYCLDVMRQLETLYVYS
HLRNDQDTTNATDQALHSRANALVAKASEAIAWFEPEVLALEDAKIWGYFDELPELSLYRHYIQQIVDNREHILPAEQEA
LLAGAGEIFGAAADTFSVLNNADLEFPVIEDEKGEKVQLSHGVYGQLLESTDRRVRKDAFEGLYKVYQQFARTFASTLST
NVKRHNYAAKVRHFESARQAALSGNHIPESVYETLVSVVNENLPLLHRYMALRKRLLNLDEMHMYDVYTPLLGESSLKYT
YEEATKEAFKALEPMGEEYLAVVKEAFENRWIDVVENKGKRSGAYSSGCYDTNPYILLNWHDTLDQLFTLVHEMGHSVHS
YFTRKNQPYVYGDYSIFLAEIASTTNENILTEYLLETQKDPKVRAFVLNHYLDGFKATVFRQTQFAEFEHFIHVEDAKGT
PLTAEFLNDYYGNLNKRYYGDAVTSDSQISYEWSRIPHFYYNYYVYQYATGFSAASALAKKILSKEENALENYLNYLKAG
NSDYPIEVMKKAGVDMTKADYLKEAMQVFAQRLDELEALVSELEK

Nucleotide


Download         Length: 1818 bp        

>NTDB_id=1155142 QML63_RS10350 WP_282013509.1 2086643..2088460(-) (pepF) [Enterococcus cecorum isolate CIRMBP-1212]
ATGTCAGAAACAAAACAATTACCATTACGTTCTGAAGTACCAGAAGAATTAACTTGGGACTTATCTGTCATTTTTAAAGA
CGATGCAGCCTTTGAAGAAGCATTTGCCGCATTGAATGATCGTTTGGCAGAAGTAGGCAACTATCAAGGAACACTAGCTA
ATGGTGCCAAAGCCTTTTTAGCAGCTTTAGAATATTGCTTAGATGTGATGCGCCAATTAGAAACGCTTTATGTTTACTCT
CATTTACGCAATGACCAAGACACTACTAATGCGACAGATCAAGCCTTGCATTCACGTGCCAATGCCTTAGTTGCTAAAGC
TAGTGAAGCCATTGCCTGGTTTGAACCTGAAGTATTAGCATTAGAGGATGCAAAAATTTGGGGTTATTTCGATGAATTAC
CAGAATTAAGTCTTTATCGCCATTATATCCAACAAATCGTGGACAATCGCGAACACATTTTACCAGCTGAACAAGAAGCA
TTATTAGCTGGTGCTGGTGAAATTTTTGGTGCTGCAGCAGATACTTTCTCTGTTTTAAACAATGCCGACTTAGAATTTCC
GGTGATTGAAGATGAAAAAGGTGAAAAAGTCCAATTATCTCATGGCGTATATGGTCAATTATTAGAAAGCACTGATCGTC
GTGTACGTAAAGATGCCTTTGAAGGTTTATATAAAGTGTACCAACAATTTGCGCGTACCTTTGCATCCACTTTAAGTACC
AATGTGAAACGCCATAACTATGCTGCAAAAGTACGTCATTTTGAATCTGCCCGTCAAGCAGCATTAAGTGGCAATCATAT
TCCTGAAAGTGTGTACGAAACTTTAGTCAGCGTGGTTAATGAAAACTTACCATTGTTACACCGCTACATGGCTTTGCGCA
AACGTTTATTAAACTTAGATGAAATGCACATGTACGATGTCTACACACCACTTTTAGGTGAAAGTTCATTGAAATATACT
TATGAAGAAGCCACCAAAGAAGCCTTCAAAGCATTAGAACCAATGGGCGAGGAATACTTAGCTGTGGTGAAAGAAGCTTT
TGAAAACCGCTGGATTGATGTGGTGGAAAATAAAGGTAAACGCAGTGGGGCTTATTCATCAGGTTGCTATGATACCAATC
CATACATCTTGTTAAACTGGCATGACACCCTAGACCAATTATTTACTTTGGTTCATGAAATGGGCCACTCTGTTCATAGT
TACTTCACACGCAAAAATCAACCATATGTATACGGTGATTACTCGATTTTCTTAGCTGAAATTGCGTCTACAACGAATGA
AAATATCTTAACTGAATATTTATTAGAAACACAAAAAGATCCTAAAGTGCGTGCCTTTGTCTTAAATCATTATCTAGATG
GCTTTAAGGCAACTGTTTTCCGTCAAACCCAATTTGCAGAATTTGAACACTTTATTCATGTGGAAGATGCAAAAGGTACC
CCATTAACTGCTGAATTCTTAAATGATTATTATGGCAACTTGAACAAACGCTACTATGGCGATGCAGTAACAAGTGATTC
ACAAATCAGCTATGAATGGTCACGTATCCCTCACTTCTACTACAATTATTATGTTTATCAATATGCAACTGGCTTTAGTG
CTGCCTCTGCCTTAGCGAAGAAGATTCTAAGCAAGGAAGAAAATGCCTTAGAAAACTACTTGAACTATCTAAAAGCTGGT
AATAGTGACTACCCAATCGAAGTCATGAAAAAAGCCGGCGTAGATATGACTAAAGCAGATTATCTAAAAGAAGCCATGCA
AGTCTTCGCACAACGCCTAGACGAACTAGAAGCACTAGTAAGTGAGCTAGAAAAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(117-186)

Peptidase family M3 (Peptidase_M3)

(207-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

57.022

97.686

0.557

Multiple sequence alignment