Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OOL12_RS14505 Genome accession   NZ_OX344719
Coordinates   2878541..2879257 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain ST20190863 isolate ST20190863     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2873541..2884257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OOL12_RS14485 - 2874635..2875585 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  OOL12_RS14490 - 2875734..2877218 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  OOL12_RS14495 - 2877215..2878174 (+) 960 WP_001253312.1 carbohydrate kinase family protein -
  OOL12_RS14500 - 2878362..2878469 (-) 108 WP_001790167.1 hypothetical protein -
  OOL12_RS14505 agrA 2878541..2879257 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OOL12_RS14510 agrC 2879276..2880568 (-) 1293 WP_264717406.1 quorum-sensing sensor histidine kinase AgrC -
  OOL12_RS14515 agrD 2880593..2880733 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  OOL12_RS14520 agrB 2880730..2881299 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  OOL12_RS14525 hld 2881589..2881669 (+) 81 WP_000046022.1 delta-hemolysin -
  OOL12_RS14530 - 2882266..2883051 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  OOL12_RS14535 - 2883412..2884038 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1154856 OOL12_RS14505 WP_000688492.1 2878541..2879257(-) (agrA) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1154856 OOL12_RS14505 WP_000688492.1 2878541..2879257(-) (agrA) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment