Detailed information NTG1154852

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: OOL12_RS11345
• Genome accession: NZ_OX344719
• Coordinates: 2261530..2262417 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ST20190863 isolate ST20190863
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2256530..2267417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OOL12_RS11315	-	2257262..2258023 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
OOL12_RS11320	-	2258268..2258723 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
OOL12_RS11325	-	2258845..2258946 (+)	102	WP_000731972.1	SE2200 family small protein	-
OOL12_RS11330	-	2259006..2260430 (-)	1425	WP_000953744.1	alkaline phosphatase	-
OOL12_RS11335	-	2260628..2260828 (+)	201	WP_000604728.1	hypothetical protein	-
OOL12_RS11340	braR	2260854..2261519 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
OOL12_RS11345	braS	2261530..2262417 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
OOL12_RS11350	-	2262525..2263280 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
OOL12_RS11355	-	2263277..2265277 (+)	2001	WP_000776751.1	ABC transporter permease	-
OOL12_RS11360	-	2265936..2266049 (+)	114	WP_011447078.1	hypothetical protein	-
OOL12_RS11365	-	2266431..2266691 (+)	261	WP_001789910.1	hypothetical protein	-
OOL12_RS11370	-	2266701..2267198 (+)	498	WP_001065268.1	glutathione peroxidase	-
OOL12_RS11375	-	2267306..2267398 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1154852 OOL12_RS11345 WP_000143419.1 2261530..2262417(+) (braS) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1154852 OOL12_RS11345 WP_000143419.1 2261530..2262417(+) (braS) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997