Detailed information NTG1154338

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AD178_RS08975
• Genome accession: NZ_OX244288
• Coordinates: 1759732..1760799 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain PT8105 isolate 2RLC4
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1754732..1765799

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AD178_RS08955 (SAMEA1463109_01807)	-	1755039..1755932 (-)	894	WP_001012092.1	ABC transporter permease	-
AD178_RS08960 (SAMEA1463109_01809)	-	1755944..1756881 (-)	938	Protein_1780	ABC transporter substrate-binding protein	-
AD178_RS08965 (SAMEA1463109_01810)	-	1757430..1758686 (+)	1257	WP_000530082.1	ISL3 family transposase	-
AD178_RS08970 (SAMEA1463109_01811)	amiF	1758795..1759721 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
AD178_RS08975 (SAMEA1463109_01812)	amiE	1759732..1760799 (-)	1068	WP_000159554.1	oligopeptide/dipeptide ABC transporter ATP-binding protein	Regulator
AD178_RS08980 (SAMEA1463109_01813)	amiD	1760808..1761734 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
AD178_RS08985 (SAMEA1463109_01814)	amiC	1761734..1763230 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
AD178_RS08990 (SAMEA1463109_01815)	amiA3	1763297..1765276 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=1154338 AD178_RS08975 WP_000159554.1 1759732..1760799(-) (amiE) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=1154338 AD178_RS08975 WP_000159554.1 1759732..1760799(-) (amiE) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAAATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541