Detailed information NTG0115394

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: RG27_RS25080
• Genome accession: NZ_CP010121
• Coordinates: 4879480..4882302 (+)
• Length: 940 a.a.
• NCBI ID: WP_000357731.1
• Uniprot ID: -
• Organism: Escherichia coli strain C4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4874480..4887302

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RG27_RS25050 (RG27_23845)	soxR	4875417..4875881 (-)	465	WP_000412424.1	redox-sensitive transcriptional activator SoxR	-
RG27_RS25055 (RG27_23850)	soxS	4875967..4876290 (+)	324	WP_000019358.1	superoxide response transcriptional regulator SoxS	-
RG27_RS25060 (RG27_23855)	pdeC	4876293..4877879 (-)	1587	WP_073462028.1	c-di-GMP phosphodiesterase PdeC	-
RG27_RS25070 (RG27_23860)	yjcB	4878309..4878590 (+)	282	WP_001295689.1	YjcB family protein	-
RG27_RS25075 (RG27_23865)	ssb	4878689..4879225 (-)	537	WP_000168305.1	single-stranded DNA-binding protein SSB1	Machinery gene
RG27_RS25080 (RG27_23870)	uvrA	4879480..4882302 (+)	2823	WP_000357731.1	excinuclease ABC subunit UvrA	Machinery gene
RG27_RS25085 (RG27_23875)	yjbR	4882337..4882693 (-)	357	WP_000155657.1	MmcQ/YjbR family DNA-binding protein	-
RG27_RS25090 (RG27_23880)	yjbQ	4882697..4883113 (-)	417	WP_000270375.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
RG27_RS25095 (RG27_23885)	aphA	4883224..4883937 (-)	714	WP_001226928.1	acid phosphatase AphA	-
RG27_RS26910	-	4884338..4884560 (+)	223	Protein_4579	hypothetical protein	-
RG27_RS25105 (RG27_23895)	tyrB	4885063..4886256 (-)	1194	WP_033870414.1	aromatic amino acid transaminase	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 103853.51 Da
• Isoelectric Point: 6.6066

>NTDB_id=115394 RG27_RS25080 WP_000357731.1 4879480..4882302(+) (uvrA) [Escherichia coli strain C4]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLSQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide

• Length: 2823 bp

>NTDB_id=115394 RG27_RS25080 WP_000357731.1 4879480..4882302(+) (uvrA) [Escherichia coli strain C4]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAACTTAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTCGGTGAGCCGCGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGTTGTCCCAGCCGGAAGGTAAACGCCTGATGCTGCTCGCACCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAAAATCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGATGATCTTT
CCCAACGTCTTGCCGAGTCGTTTGAAACTGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTTGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCTAATTTCGCCTGCCCAATTTGCGGCTACAGTATGCGCGAGCTGGAGCCGCGACT
GTTTTCGTTTAACAACCCGGCAGGGGCCTGCCCGACCTGTGACGGCCTTGGCGTGCAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAACTGTCGCTGGCTGGCGGTGCGATCCGAGGCTGGGATCGCCGCAACTTCTATTACTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGCGAAGAATTAGCCAAGTTT
ATCAGCAATCGCCCGTGCGCCAGCTGCGAAGGGACGCGTCTGCGTCGAGAAGCGCGCCATGTGTATGTCGAGAATACGCC
GCTGCCTGCTATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGAGCTA
AGATTGCGGAAAAAATTCTTAAAGAGATTGGCGATCGCCTGAAATTCCTCGTTAACGTAGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAGACACTTTCTGGCGGTGAAGCCCAGCGTATCCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTACGTGCTGGACGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGACCATGTGATCGACATT
GGCCCGGGCGCAGGTGTACACGGCGGTGAAGTGGTCGCAGAAGGTCCACTGGAAGCGATTATGGCAGTGCCTGAATCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGTAATAACCTGAAAGACGTGACGCTGACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCAGCGACCTATACCGGCGTGTTTACGCCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCGGGACGTTTCAGCTTTAACGTCCGTGGCGGGCGCTGCGAAGCCTGTCAGGGCGATGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGATATCTACGTGCCGTGCGACCAGTGCAAAGGTAAACGCTATAACCGCG
AAACGCTGGAAATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTCGGGCAGTCCGC
AACCACGCTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACACTGT
ATATTCTTGATGAGCCGACCACCGGTTTGCACTTCGCCGATATTCAGCAACTGCTCGACGTGCTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTGATTGAACACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGCGGCGGCGAGATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCAC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (290-399)

• ABC transporter (ABC_tran) (806-860)

• UvrA interaction domain (UvrA_inter) (130-237)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.37	100	0.576
uvrA	Streptococcus pneumoniae TIGR4	57.37	100	0.576
uvrA	Streptococcus pneumoniae D39	57.37	100	0.576