Detailed information NTG1152108

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: MMH06_RS04895
• Genome accession: NZ_OV904788
• Coordinates: 916975..917685 (-)
• Length: 236 a.a.
• NCBI ID: WP_000760673.1
• Uniprot ID: A0A062WVH4
• Organism: Streptococcus pneumoniae strain RMV7 isolate RMV7domi
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	913784..916818	916975..917685	flank	157

Gene organization within MGE regions

Location: 913784..917685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MMH06_RS04880 (IONPJBJN_00956)	-	913784..913969 (-)	186	Protein_920	transposase	-
MMH06_RS04885 (IONPJBJN_00957)	-	914162..915508 (-)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
MMH06_RS04890	-	915675..916818 (-)	1144	Protein_922	transposase	-
MMH06_RS04895 (IONPJBJN_00961)	treR	916975..917685 (-)	711	WP_000760673.1	trehalose operon repressor	Regulator

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27607.78 Da
• Isoelectric Point: 8.9698

>NTDB_id=1152108 MMH06_RS04895 WP_000760673.1 916975..917685(-) (treR) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide

• Length: 711 bp

>NTDB_id=1152108 MMH06_RS04895 WP_000760673.1 916975..917685(-) (treR) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTCATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAGAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (89-227)

3D structure

• AlphaFold DB: A0A062WVH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	59.322	100	0.593