Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MD993_RS09410 Genome accession   NZ_OV648025
Coordinates   1981833..1982549 (+) Length   238 a.a.
NCBI ID   WP_000688486.1    Uniprot ID   A0A7U7PWL0
Organism   Staphylococcus argenteus isolate 20S00001-1_long     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1976833..1987549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MD993_RS09380 - 1977390..1978016 (+) 627 WP_031787858.1 nitroreductase family protein -
  MD993_RS09385 - 1978117..1978902 (+) 786 WP_031787859.1 carbon-nitrogen family hydrolase -
  MD993_RS12980 hld 1979423..1979503 (-) 81 WP_000046023.1 delta-hemolysin -
  MD993_RS09395 - 1979792..1980355 (+) 564 WP_031787860.1 accessory gene regulator AgrB -
  MD993_RS09400 agrD 1980357..1980497 (+) 141 WP_001093930.1 cyclic lactone autoinducer peptide AgrD -
  MD993_RS09405 agrC 1980522..1981814 (+) 1293 WP_031787861.1 quorum-sensing sensor histidine kinase AgrC -
  MD993_RS09410 agrA 1981833..1982549 (+) 717 WP_000688486.1 quorum-sensing response regulator AgrA Regulator
  MD993_RS09415 - 1982902..1983861 (-) 960 WP_031787862.1 carbohydrate kinase -
  MD993_RS09420 - 1983858..1985342 (-) 1485 WP_000141408.1 sucrose-6-phosphate hydrolase -
  MD993_RS09425 - 1985491..1986441 (-) 951 WP_031787863.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27894.87 Da        Isoelectric Point: 5.8625

>NTDB_id=1151912 MD993_RS09410 WP_000688486.1 1981833..1982549(+) (agrA) [Staphylococcus argenteus isolate 20S00001-1_long]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDDPYEVLEQSKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1151912 MD993_RS09410 WP_000688486.1 1981833..1982549(+) (agrA) [Staphylococcus argenteus isolate 20S00001-1_long]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAACCTATGGAAATTGCCCTCGCAACTGATGATCCTTATGAGGTGCTTGAGCAATCTAAAAATATGAATGATATAG
GTTGTTACTTTTTAGATATTCAACTTTCAACAGACATTAATGGTATTAAATTAGGTAGTGAAATACGTAAGCATGACCCT
GTTGGCAATATAATATTTGTTACTAGTCATAGTGAACTTACTTATTTAACATTTGTCTACAAAGTTGCAGCAATGGATTT
TATTTTTAAAGATGATCCTGCTGAATTAAAAACACGAATTATAGATTGTCTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATAGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATACGATGATATTATG
TTTTTCGAATCATCTACCAAATCGCATAGACTCATCGCCCATTTAGATAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAATTGAGTCAATTAGATGATCGTTTTTTCAGATGTCATAATAGTTTTGTTGTCAATCGTCATAATATCGAATCCATTG
ATTCGAAAGAACGAATTGTCTATTTTAAAAATAAAGAACATTGTTATGCATCGGTAAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PWL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

98.739

100

0.987

Multiple sequence alignment