Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DYY95_RS10750 Genome accession   NZ_LT996891
Coordinates   2113777..2114493 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus isolate 24117-WT     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2108777..2119493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYY95_RS10730 - 2109869..2110819 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  DYY95_RS10735 - 2110968..2112452 (+) 1485 WP_000141411.1 sucrose-6-phosphate hydrolase -
  DYY95_RS10740 - 2112449..2113408 (+) 960 WP_001253291.1 carbohydrate kinase family protein -
  DYY95_RS10745 - 2113596..2113705 (-) 110 Protein_2013 hypothetical protein -
  DYY95_RS10750 agrA 2113777..2114493 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  DYY95_RS10755 agrC 2114512..2115795 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  DYY95_RS10760 agrD 2115825..2115968 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  DYY95_RS10765 - 2115952..2116587 (-) 636 WP_001641623.1 accessory gene regulator AgrB -
  DYY95_RS14345 hld 2116823..2116903 (+) 81 WP_000046022.1 delta-hemolysin -
  DYY95_RS10775 - 2117503..2118288 (-) 786 WP_000867950.1 carbon-nitrogen family hydrolase -
  DYY95_RS10780 - 2118649..2119275 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=1150525 DYY95_RS10750 WP_000688498.1 2113777..2114493(-) (agrA) [Staphylococcus aureus isolate 24117-WT]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1150525 DYY95_RS10750 WP_000688498.1 2113777..2114493(-) (agrA) [Staphylococcus aureus isolate 24117-WT]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment